New conductive devices for application in electrochemical sensing and biosensing

• Grant number: 17/21898-6
• Support Opportunities: Regular Research Grants
• Duration: February 01, 2018 - January 31, 2020
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Bruno Campos Janegitz
• Grantee: Bruno Campos Janegitz
• Host Institution: Centro de Ciências Agrárias (CCA). Universidade Federal de São Carlos (UFSCAR). Araras , SP, Brazil

Abstract

The electrochemical sensors and biosensors can facilitate the resolution of modern problems relatively quickly. The need for new methodologies and improvements in disease detection processes, aiming for accuracy and speed, leads to the development of new technologies. Therefore, analysis of diseases that would take weeks can be carried out in a few hours, with high accuracy and reliability. Based on screen-printing and electrochemical techniques, we aim to develop disposable electrodes with relative low cost by using environmentally friendly materials. In this context, the objective of this project is a proposal of new electrochemical sensors and biosensors, by using disposables, versatiles and low cost platforms such as PET and paper. In a first step, it will prepared conductive inks with polym,ers and carbon materials. In a second moment, electrodes will be prepared from the electro-spinning technique. As a form of application, we propose the use of these disposable electrodes in the electrochemical detection of biomarkers related to Alzheimer's and Parkinson's diseases. It is expected to obtain devices with high sensitivity, wide linear ranges, stable, with low detection limits and robust. (AU)

Scientific publications

(18)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE OLIVEIRA, GABRIELA CAROLINA MAURUTO; CAMARGO, JESSICA ROCHA; VIEIRA, NIRTON CRISTI SILVA; JANEGITZ, BRUNO CAMPOS. A new disposable electrochemical sensor on medical adhesive tape. Journal of Solid State Electrochemistry, v. 24, n. 10, JUN 2020. (17/21898-6, 17/21097-3, 17/17572-8, 19/23177-0)

OLIANI PEDRO DA SILVA, VINICIUS APARECIDO; DE FREITAS, RAFAELA CRISTINA; DE OLIVEIRA, PAULO ROBERTO; MOREIRA, ROGER CARDOSO; MARCOLINO-JUNIOR, LUIZ HUMBERTO; BERGAMINI, MARCIO FERNANDO; COLTRO, WENDELL K. T.; JANEGITZ, BRUNO CAMPOS. Microfluidic paper-based device integrated with smartphone for point-of-use colorimetric monitoring of water quality index. MEASUREMENT, v. 164, NOV 2020. (17/21898-6, 19/01844-4, 17/21097-3)

PRADEL-FILHO, LAURO A.; ANDREOTTI, ISABELA A. A.; CARVALHO, JEFFERSON H. S.; ARAUJO, DIELE A. G.; ORZARI, LUIZ O.; GATTI, ALEXANDRE; TAKEUCHI, REGINA M.; SANTOS, ANDRE L.; JANEGITZ, BRUNO C.. Glass varnish-based carbon conductive ink: A new way to produce disposable electrochemical sensors. SENSORS AND ACTUATORS B-CHEMICAL, v. 305, FEB 15 2020. (16/12697-4, 17/21898-6, 17/21097-3, 19/04085-7)

CAMARGO, JESSICA R.; ANDREOTTI, ISABELLA A. A.; KALINKE, CRISTIANE; HENRIQUE, JULIA M.; BONACIN, JULIANO A.; JANEGITZ, BRUNO C.. Waterproof paper as a new substrate to construct a disposable sensor for the, electrochemical determination of paracetamol and melatonin. Talanta, v. 208, FEB 1 2020. (17/21898-6, 18/02162-1, 17/21097-3, 19/00473-2, 13/22127-2)

RAYMUNDO-PEREIRA, PAULO A.; BACCARIN, MARINA; OLIVEIRA, JR., OSVALDO N.; JANEGITZ, BRUNO C.. Thin Films and Composites Based on Graphene for Electrochemical Detection of Biologically-relevant Molecules. Electroanalysis, v. 30, n. 9, p. 1888-1896, SEP 2018. (16/01919-6, 17/21898-6, 13/14262-7)

ZAMBIANCO, NAIARA ALANA; SILVA, TIAGO ALMEIDA; ZANIN, HUDSON; FATIBELLO-FILHO, ORLANDO; JANEGITZ, BRUNO CAMPOS. Novel electrochemical sensor based on nanodiamonds and manioc starch for detection of diquat in environmental samples. DIAMOND AND RELATED MATERIALS, v. 98, OCT 2019. (17/21898-6, 17/11958-1, 17/21097-3, 14/02163-7)

ITKES, MARINA P. M.; DE OLIVEIRA, GEISER G.; SILVA, TIAGO ALMEIDA; FATIBELLO-FILHO, ORLANDO; JANEGITZ, BRUNO C.. Voltammetric sensing of fenitrothion in natural water and orange juice samples using a single-walled carbon nanohorns and zein modified sensor. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 840, p. 21-26, MAY 1 2019. (17/21898-6, 17/24618-4, 11/13312-5)

BRAZACA, LAIS CANNIATTI; SAMPAIO, ISABELLA; ZUCOLOTTO, VALTENCIR; JANEGITZ, BRUNO CAMPOS. Applications of biosensors in Alzheimer's disease diagnosis. Talanta, v. 210, APR 1 2020. (17/21898-6, 17/21097-3, 15/02623-0, 18/19750-3)

MAURUTO DE OLIVEIRA, GABRIELA C.; DE SOUZA CARVALHO, JEFFERSON HENRIQUE; BRAZACA, LAIS CANNIATTI; SILVA VIEIRA, NIRTON CRISTI; JANEGITZ, BRUNO CAMPOS. Flexible platinum electrodes as electrochemical sensor and immunosensor for Parkinson's disease biomarkers. BIOSENSORS & BIOELECTRONICS, v. 152, MAR 15 2020. (17/17572-8, 18/07508-3, 19/04085-7, 17/21097-3, 18/19750-3, 17/21898-6)

KALINKE, CRISTIANE; NEUMSTEIR, NAILE VACILOTTO; APARECIDO, GABRIEL DE OLIVEIRA; DE BARROS FERRAZ, THIAGO VASCONCELOS; DOS SANTOS, PAMYLA LAYENE; JANEGITZ, BRUNO CAMPOS; BONACIN, JULIANO ALVES. Comparison of activation processes for 3D printed PLA-graphene electrodes: electrochemical properties and application for sensing of dopamine. ANALYST, v. 145, n. 4, p. 1207-1218, FEB 21 2020. (17/23960-0, 17/21898-6, 17/21097-3, 19/00473-2, 13/22127-2)

JODAR, LETICIA VIEIRA; ORZARI, LUIZ OTAVIO; ORTOLANI, TULIO STORTI; ASSUMPCAO, MONICA H. M. T.; VICENTINI, FERNANDO C.; JANEGITZ, BRUNO C.. Electrochemical Sensor Based on Casein and Carbon Black for Bisphenol A Detection. Electroanalysis, v. 31, n. 11, JULY 2019. (15/19099-2, 17/21898-6)

ORZARI, LUIZ O.; SANTOS, FABRICIO A.; JANEGITZ, BRUNO C.. Manioc starch thin film as support of reduced graphene oxide: A novel architecture for electrochemical sensors. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 823, p. 350-358, AUG 15 2018. (17/21898-6, 15/19099-2, 16/12697-4)

ORTOLANI, TULIO S.; PEREIRA, TAMIRES S.; ASSUMPCAO, MONICA H. M. T.; VICENTINI, FERNANDO C.; DE OLIVEIRA, GEISER GABRIEL; JANEGITZ, BRUNO C.. Electrochemical sensing of purines guanine and adenine using single-walled carbon nanohorns and nanocellulose. Electrochimica Acta, v. 298, p. 893-900, MAR 1 2019. (17/21898-6)

ORZARI, LUIZ OTAVIO; DE FREITAS, RAFAELA CRISTINA; DE ARAUJO ANDREOTTI, ISABELA APARECIDA; GATTI, ALEXANDRE; JANEGITZ, BRUNO CAMPOS. A novel disposable self-adhesive inked paper device for electrochemical sensing of dopamine and serotonin neurotransmitters and biosensing of glucose. BIOSENSORS & BIOELECTRONICS, v. 138, AUG 1 2019. (17/21898-6, 16/12697-4)

DOS SANTOS, FABRICIO A.; VIEIRA, NIRTON C. S.; ZAMBIANCO, NAIARA A.; JANEGITZ, BRUNO C.; ZUCOLOTTO, VALTENCIR. The layer-by-layer assembly of reduced graphene oxide films and their application as solution-gated field-effect transistors. Applied Surface Science, v. 543, MAR 30 2021. (17/21898-6, 18/07508-3, 17/21097-3)

RAYMUNDO-PEREIRA, PAULO A.; SILVA, TIAGO A.; CAETANO, FABIO R.; RIBOVSKI, LAIS; ZAPP, EDUARDO; BRONDANI, DANIELA; BERGAMINI, MARCIO F.; MARCOLINO, JR., LUIZ H.; BANKS, CRAIG E.; OLIVEIRA, JR., OSVALDO N.; et al. Polyphenol oxidase-based electrochemical biosensors: A review. Analytica Chimica Acta, v. 1139, p. 198-221, DEC 1 2020. (16/01919-6, 18/22214-6, 17/21097-3, 17/21898-6, 20/01050-5)

DE ARAUJO ANDREOTTI, ISABELA APARECIDA; ORZARI, LUIZ OTAVIO; CAMARGO, JESSICA ROCHA; FARIA, RONALDO CENSI; MARCOLINO-JUNIOR, LUIZ HUMBERTO; BERGARNINI, MARCIO FERNANDO; GATTI, ALEXANDRE; JANEGITZ, BRUNO C.. Disposable and flexible electrochemical sensor made by recyclable material and low cost conductive ink. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 840, p. 109-116, MAY 1 2019. (17/21898-6, 16/12697-4, 18/02162-1)

VIDAL RAMOS, MATHEUS MESQUITA; CARVALHO, JEFFERSON H. S.; DE OLIVEIRA, PAULO ROBERTO; JANEGITZ, BRUNO CAMPOS. Determination of serotonin by using a thin film containing graphite, nanodiamonds and gold nanoparticles anchored in casein. MEASUREMENT, v. 149, JAN 2020. (17/21898-6, 19/01844-4, 17/21097-3)

Filed patent(s) as a result of this research project