Multi-user equipment approved in grant 2017/06216-6: ultra high performance liquid chromatograph

• Grant number: 18/01786-1
• Support Opportunities: Multi-user Equipment Program
• Start date: March 01, 2018
• End date: February 28, 2025
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Cristiano Soleo de Funari
• Grantee: Cristiano Soleo de Funari
• Host Institution: Faculdade de Ciências Agronômicas (FCA). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil
• Associated research grant: 17/06216-6 - Development of green analytical methodologies in the search for high-added value organic compounds in agricultural waste, AP.JP
• EMU web page: https://www.fca.unesp.br/#!/pesquisa/laboratorio-central/equipamentos-e-tecnicas-disponiveis/
• Type of equipment: Caracterização de Materiais - Análises Químicas - Cromatrografia líquida
• Manufacturer: Shimadzu
• Model: Nexera UC

Abstract

It is estimated that a quarter of the approximately 140 billion tons of agricultural biomass produced per year worldwide is produced in Brazil, and that more than 30% of the total waste produced in this country are agricultural wastes. According to the United Nations, there is the need to intensify research on technologies for converting agricultural waste into useful resources to society. The search for compounds of interest in waste through advanced value-added strategies based on green technologies, before adding them to low value-added products, has been seen as a way to preserve environmental resources and as a strategy for diversify the generation of products from a single feedstock. In this project, the proponent planned to take advantage of his previous experiences in green chemistry applied to natural products and analytical chemistry, acquired in Brazil and abroad (he spent about 3 years between Spain, Italy, Suisse and Australia), in academia and in industry, on the chemical investigation of agricultural waste. The means of investigation theirselves will be object of study, since analytical techniques are an important target for the application of principles of sustainability (nowadays, the ends cannot justify the means!). Natural deep eutectic solvents (NADES) and biodegradable low toxicity solvents will be investigated as extractor medias and mobile phase modifiers, whereas ultra-high performance liquid chromatography at reduced flow rates will be preferably employed as separation technique. The project execution and the acquired results will be used to boost the teaching of sustainability principles and practices for students of Engineering of Bioprocesses and Biotechnology" and for interns and graduate students linked to the newly created Department of Bioprocesses and Biotechnology and GreenBiotech Research Group to which the proponent is affiliated. A team of young scientists from Brazil, Australia and Holland operating in different subfields of chemistry has been strategically established to overcome challenges of the project. (AU)

Scientific publications

(6)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DA SILVA, MARIANA RODRIGUES; BRAGAGNOLO, FELIPE SANCHEZ; CARNEIRO, RENATO LAJARIM; CARVALHO PEREIRA, ISABELA DE OLIVEIRA; AQUINO RIBEIRO, JOSE ANTONIO; RODRIGUES, CLENILSON MARTINS; JELLEY, REBECCA E.; FEDRIZZI, BRUNO; FUNARI, CRISTIANO SOLEO. Metabolite characterization of fifteen by-products of the coffee production chain: From farm to factory. Food Chemistry, v. 369, FEB 1 2022. (18/21943-4, 17/06216-6, 18/01786-1, 18/21128-9)

SOUZA, OTAVIO AGUIAR; RAMALHAO, VICTORIA GIOVANNA DA SILVA; TRENTIN, LUCAS DE MELO; FUNARI, CRISTIANO SOLEO; CARNEIRO, RENATO LAJARIM; BOLZANI, VANDERLAN DA SILVA; RINALDO, DANIEL. Combining natural deep eutectic solvent and microwave irradiation towards the eco-friendly and optimized extraction of bioactive phenolics from Eugenia uniflora L.. SUSTAINABLE CHEMISTRY AND PHARMACY, v. 26, p. 16-pg., 2022-05-01. (18/01786-1, 14/50926-0, 16/08179-8)

SANCHEZ BRAGAGNOLO, FELIPE; SOCAS-RODRIGUEZ, BARBARA; MENDIOLA, JOSE A.; CIFUENTES, ALEJANDRO; SOLEO FUNARI, CRISTIANO; IBANEZ, ELENA. Pressurized natural deep eutectic solvents: An alternative approach to agro-soy by-products. FRONTIERS IN NUTRITION, v. 9, p. 14-pg., 2022-09-08. (14/50926-0, 20/09500-0, 18/21128-9, 17/06216-6, 18/01786-1)

SARTORI, LEONARDO DE OLIVEIRA; SOUZA, AMAURI ALVES; BRAGAGNOLO, FELIPE SANCHEZ; FORTUNA, GABRIEL CASSIA; GIARDINI BONFIM, FILIPE PEREIRA; RODRIGUES SARNIGHAUSEN, VALERIA CRISTINA; CARNEIRO, RENATO LAJARIM; FUNARI, CRISTIANO SOLEO. An efficient, fast, and green procedure to quantify alpha- and beta-acids and xanthohumol in hops and their derived products. Food Chemistry, v. 373, n. B, MAR 30 2022. (17/06216-6, 18/01786-1, 19/27066-8, 18/21128-9, 20/00484-1)

ASSIRATI, JULIA; RINALDO, DANIEL; RABELO, SARITA CANDIDA; BOLZANI, VANDERLAN DA SILVA; HILDER, EMILY FRANCES; FUNARI, CRISTIANO SOLEO. A green, simplified, and efficient experimental setup for a high-throughput screening of agri-food by-products - From polar to nonpolar metabolites in sugarcane solid residues. Journal of Chromatography A, v. 1634, DEC 20 2020. (18/50025-3, 17/06216-6, 18/09886-5, 18/01786-1, 14/50926-0)

SANCHEZ BRAGAGNOLO, FELIPE; ALVAREZ-RIVERA, GERARDO; BREITKREITZ, MARCIA CRISTINA; IBANEZ, ELENA; CIFUENTES, ALEJANDRO; FUNARI, CRISTIANO SOLEO. Metabolite Profiling of Soy By-Products: A Comprehensive Approach. Journal of Agricultural and Food Chemistry, v. 70, n. 23, p. 21-pg., 2022-06-15. (18/21128-9, 14/50926-0, 17/06216-6, 18/01786-1, 20/09500-0)