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Advanced glycation in macrophages decreases the content of the HDL - ABCA-1 and ABCG-1 - receptors and induces intracellular 7-ketocholesterol accumulation

Grant number: 07/59710-6
Support Opportunities:Scholarships in Brazil - Doctorate
Effective date (Start): June 01, 2008
Effective date (End): November 30, 2011
Field of knowledge:Health Sciences - Medicine - Medical Clinics
Principal Investigator:Edna Regina Nakandakare
Grantee:Rodrigo Tallada Iborra
Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil
News published in Agência FAPESP Newsletter about the scholarship:
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Scientific publications (4)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
MACHADO-LIMA, ADRIANA; IBORRA, RODRIGO T.; PINTO, RAPHAEL S.; SARTORI, CAMILA H.; OLIVEIRA, ERIKA R.; NAKANDAKARE, EDNA R.; STEFANO, JOSE T.; GIANNELLA-NETO, DANIEL; CORREA-GIANNELLA, MARIA LUCIA C.; PASSARELLI, MARISA. Advanced glycated albumin isolated from poorly controlled type 1 diabetes mellitus patients alters macrophage gene expression impairing ABCA-1-mediated reverse cholesterol transport. DIABETES-METABOLISM RESEARCH AND REVIEWS, v. 29, n. 1, p. 66-76, . (09/53869-9, 07/59710-6)
MACHADO-LIMA, ADRIANA; IBORRA, RODRIGO T.; PINTO, RAPHAEL S.; CASTILHO, GABRIELA; SARTORI, CAMILA H.; OLIVEIRA, ERIKA R.; OKUDA, LIGIA S.; NAKANDAKARE, EDNA R.; GIANNELLA-NETO, DANIEL; MACHADO, UBIRATAN F.; et al. In Type 2 Diabetes Mellitus Glycated Albumin Alters Macrophage Gene Expression Impairing ABCA1-Mediated Cholesterol Efflux. Journal of Cellular Physiology, v. 230, n. 6, p. 1250-1257, . (09/53869-9, 07/59710-6)
IBORRA, RODRIGO T.; MACHADO-LIMA, ADRIANA; CASTILHO, GABRIELA; NUNES, VALERIA S.; ABDALLA, DULCINEIA S. P.; NAKANDAKARE, EDNA R.; PASSARELLI, MARISA. Advanced Glycation in macrophages induces intracellular accumulation of 7-ketocholesterol and total sterols by decreasing the expression of ABCA-1 and ABCG-1. LIPIDS IN HEALTH AND DISEASE, v. 10, . (09/53869-9, 07/59710-6)
MACHADO, JULIANA T.; IBORRA, RODRIGO T.; FUSCO, FERNANDA B.; CASTILHO, GABRIELA; PINTO, RAPHAEL S.; MACHADO-LIMA, ADRIANA; NAKANDAKARE, EDNA R.; SEGURO, ANTONIO C.; SHIMIZU, MARIA H.; CATANOZI, SERGIO; et al. N-acetylcysteine prevents endoplasmic reticulum stress elicited in macrophages by serum albumin drawn from chronic kidney disease rats and selectively affects lipid transporters, ABCA-1 and ABCG-1. ATHEROSCLEROSIS, v. 237, n. 1, p. 343-352, . (07/59710-6)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
IBORRA, Rodrigo Tallada. Advanced Glycation in macrophages decreases the content of the HDL receptor ABCA-1 and ABCG-1 - and induces intracellular accumulation of 7-ketocholesterol. 2011. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Medicina (FM/SBD) São Paulo.

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