Synthetic Applications of the Petasis Reactions of N-acyliminium Ions. Use of enecarbamates in organocatalysis and in the synthesis of sphingosines analogues.

• Grant number: 08/00122-0
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: August 01, 2008
• End date: April 30, 2012
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Carlos Roque Duarte Correia
• Grantee: Pablo David Grigol Martinez
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

This proposal intend to prepare nitrogenated heterocycles 2,3-disubstituted with syn stereochemistry through Petasis reaction using N-acyliminium ions generated in situ from lactams. This proposal has either the objective to sinthesize stereoselectively alkaloids with farmacological interest.

Scientific publications

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

GODOI, MARLA N.; DE AZAMBUJA, FRANCISCO; MARTINEZ, PABLO DAVID G.; MORGON, NELSON H.; SANTOS, VANESSA G.; REGIANI, THAIS; LESAGE, DENIS; DOSSMANN, HELOISE; COLE, RICHARD B.; EBERLIN, MARCOS N.; et al. Revisiting the Intermolecular Fujiwara Hydroarylation of Alkynes. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, v. 2017, n. 13, p. 1794-1803, APR 3 2017. (10/00257-3, 08/00122-0, 10/11068-7, 11/23832-6)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

MARTINEZ, Pablo David Grigol. Endocyclic enecarbamates as substrates in organocatalysis: approaches to sphingoid bases synthesis and bulgecinine analogue. 2013. Doctoral Thesis - Universidade Estadual de Campinas (UNICAMP). Instituto de Química Campinas, SP.