| Grant number: |
10/15604-0
|
| Support type: | Scholarships in Brazil - Post-Doctorate |
| Effective date (Start): |
December 01, 2010
|
| Effective date (End): |
November 30, 2013
|
| Field of knowledge: | Health Sciences
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Medicine
-
Psychiatry |
|
| Principal Investigator: | Geraldo Busatto Filho |
| Grantee: | Paulo Jannuzzi Cunha |
|
| Home Institution: |
Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil
|
|
Abstract
Despite the high prevalence of children and adolescent maltreatment (CAM), research studies evaluating the effects of maltreatment on brain anatomy and neuropsychological functioning in this population are still limited. There is evidence of reduced volume of the corpus callosum (CC) in association with CAM, but no study to date has evaluated the association between abnormalities of white matter (WM) tracts in the CC, interhemispheric transfer of information, and decision making, taking into account the period when the maltreatment has began. The aim of this study is to investigate the relationship between integrity, size and deformity of the CC, interhemispheric transfer of somatosensory information, and decision making in maltreated children and adolescents. The sample consists of 100 children and adolescents, between 8-17 years old, divided in 60 maltreated and 40 control individuals. They will undergo brain magnetic resonance imaging (MRI) scanning; white matter integrity, regional volumes, and surface patterns of the CC will be determined by methods combining Diffusion Tensor Imaging (DTI), Voxel-Based Morphometry (VBM), and Surface-Based Modeling (SBM), respectively. Neuropsychological assessment will consist of the Crossed Finger Localization Test (CFLT), Wechsler Intelligence Scale for Children - Third Edition (WISC-III), and the Iowa Gambling Task (IGT). We aim to detect early abnormalities that may predispose individuals who suffered CAM to later psychopathological and cognitive impairments, in the hope that such data may reinforce the need to generate future preventive and rehabilitation interventions in Public Health. (AU)
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| News published in Agência FAPESP Newsletter about the scholarship: |
| Study contests use of smoked cannabis in treatment of cocaine addiction
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| Cocaine use during adolescence is even more harmful than during adulthood
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| Cognitive rehabilitation helps to treat chemical dependents
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Scientific publications
(8)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DE OLIVEIRA JUNIOR, HERCILIO PEREIRA;
DI GONCALVES, PRISCILA;
OMETTO, MARIELLA;
DOS SANTOS, BERNARDO;
MALBERGIER, ANDRE;
AMARAL, RICARDO;
NICASTRI, SERGIO;
DE ANDRADE, ARTHUR GUERRA;
CUNHA, PAULO JANNUZZI.
Distinct effects of cocaine and cocaine plus cannabis on neurocognitive functioning and abstinence: A six-month follow-up study.
DRUG AND ALCOHOL DEPENDENCE,
v. 205,
DEC 1 2019.
Web of Science Citations: 0.
LIM, DANIELLE RUIZ;
GONCALVES, PRISCILA DIB;
OMETTO, MARIELLA;
MALBERGIER, ANDRE;
AMARAL, RICARDO ABRANTES;
DOS SANTOS, BERNARDO;
CAVALLET, MIKAEL;
CHAIM-AVANCINI, TIFFANY;
SERPA, MAURICIO HENRIQUES;
KOBUTI FERREIRA, LUIZ ROBERTO;
DE SOUZA DURAN, FABIO LUIS;
ZANETTI, MARCUS VINICIUS;
NICASTR, SERGIO;
BUSATTO, GERALDO FILHO;
ANDRAD, ARTHUR GUERRA;
CUNH, PAULO JANNUZZI.
The role of neurocognitive functioning, substance use variables and the DSM-5 severity scale in cocaine relapse: A prospective study.
DRUG AND ALCOHOL DEPENDENCE,
v. 197,
p. 255-261,
APR 1 2019.
Web of Science Citations: 2.
OLIVEIRA, HERCILIO P.;
GONCALVES, PRISCILA D.;
OMETTO, MARIELLA;
SANTOS, BERNARDO;
MALBERGIER, ANDRE;
AMARAL, RICARDO;
NICASTRI, SERGIO;
ANDRADE, ARTHUR G.;
CUNHA, PAULO J.
The Route of Administration Exacerbates Prefrontal Functional Impairments in Crack Cocaine Users.
PSYCHOLOGY OF ADDICTIVE BEHAVIORS,
v. 32,
n. 7,
p. 812-820,
NOV 2018.
Web of Science Citations: 1.
LOPES, BRUNA MAYARA;
GONCALVES, PRISCILA DIB;
OMETTO, MARIELLA;
DOS SANTOS, BERNARDO;
CAVALLET, MIKAEL;
CHAIM-AVANCINI, TIFFANY MOUKBEL;
SERPA, MAURICIO HENRIQUES;
NICASTRI, SERGIO;
MALBERGIER, ANDRE;
BUSATTO, GERALDO F.;
DE ANDRADE, ARTHUR GUERRA;
CUNHA, PAULO JANNUZZI.
Distinct cognitive performance and patterns of drug use among early and late onset cocaine users.
ADDICTIVE BEHAVIORS,
v. 73,
p. 41-47,
OCT 2017.
Web of Science Citations: 7.
VIDAL MILIONI, ANA LUIZA;
CHAIM, TIFFANY MOUKBEL;
CAVALLET, MIKAEL;
DE OLIVEIRA, NATHALYA MOLEDA;
ANNES, MARCO;
DOS SANTOS, BERNARDO;
LOUZA, MARIO;
DA SILVA, MARIA APARECIDA;
MIGUEL, CARMEN SILVIA;
SERPA, MAURICIO HENRIQUES;
ZANETTI, MARCUS V.;
BUSATTO, GERALDO;
CUNHA, PAULO JANNUZZI.
High IQ May ``Mask{''} the Diagnosis of ADHD by Compensating for Deficits in Executive Functions in Treatment-Naive Adults With ADHD.
JOURNAL OF ATTENTION DISORDERS,
v. 21,
n. 6,
p. 455-464,
APR 2017.
Web of Science Citations: 10.
OMETTO, MARIELLA;
DE OLIVEIRA, PAULA APPROBATO;
MILIONI, ANA LUIZA;
DOS SANTOS, BERNARDO;
SCIVOLETTO, SANDRA;
BUSATTO, GERALDO F.;
NUNES, PAULA V.;
CUNHA, PAULO JANNUZZI.
Social skills and psychopathic traits in maltreated adolescents.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY,
v. 25,
n. 4,
p. 397-405,
APR 2016.
Web of Science Citations: 6.