Scholarship 11/02527-0 - Fabaceae, Química de produtos naturais - BV FAPESP
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Chemical and pharmacological study of Machaerium hirtum (Fabaceae)

Grant number: 11/02527-0
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Start date until: August 01, 2011
End date until: July 31, 2014
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Organic Chemistry
Principal Investigator:Miriam Sannomiya
Grantee:Nelly Cristina Venite de Souza Maria
Host Institution: Escola de Artes, Ciências e Humanidades (EACH). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The main of this project is contribute to the knowledge of the potentiality of the some Machaerium species from the Brazilian Cerrado by a chemical-pharmacological study, in other words, isolation and identification of the compounds presented in the vegetable extracts together with pharmacological assays to the antiulcer, anti-inflamatory/analgesic, anti-mutagenic and mutagenic activities. According to the literature, some Machaerium species (Fabaceae) are ethnopharmacologic used like as Machaerium hirtum (vell.) Stellfedl., it is a plant which barks are employed popularly against diarrhoea, cough and cancer. It is popularly known as "adolfo and bico-de andorinha". Despite of it, no data until now can be observed approaching the chemistry or pharmacological studies with this species.

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