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Aminoacid metabolism and aging in Saccharomyces cerevisiae

Grant number: 11/13506-4
Support type:Scholarships in Brazil - Doctorate (Direct)
Effective date (Start): September 01, 2011
Effective date (End): March 31, 2013
Field of knowledge:Biological Sciences - Biochemistry - Metabolism and Bioenergetics
Principal Investigator:Alicia Juliana Kowaltowski
Grantee:Phillipe Pessoa de Santana
Home Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Associated research grant:10/51906-1 - Mitochondrial bioenergetics, ion transport, redox state and DNA metabolism, AP.TEM


S. cerevisiae are an interesting experimental model to study aging and the beneficial effects of calorie restriction. We recently found, using proteomics, that calorie restriction and aging significantly change the expression of proteins related to aminoacid metabolism. This project aims to study the effects of calorie restriction and aging on aminoacid metabolism. (AU)