Microorganisms, plants and animals produce a wide range of compounds that cold act as drugs, pigments, fragrances, flavorings and cosmetics. The biosynthesis of such metabolites is mediated by multienzymes complexes acting since the cabonic chain extension to the post-modifying steps. The versatility of such enzymes could be applicable to bioconversions of xenobiotics in order to obtain chiral blocks. We intend to study in this project the capacity of strptomyces strains to promote biotransformations mediated by monooxigenases, oxido-reductases and hydrolysis using whole cell systems.
News published in Agência FAPESP Newsletter about the scholarship: