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MR Enterography in Small-Bowel Crohn's Disease.

Grant number: 11/13946-4
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): November 01, 2011
Effective date (End): October 31, 2012
Field of knowledge:Health Sciences - Medicine - Medical Radiology
Principal researcher:Nelson Marcio Gomes Caserta
Grantee:Marco Antônio Mendes Rocha
Home Institution: Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

Crohn's disease is an idiopathic granulomatous lesion of the gastrointestinal tract which may affect any segment of the digestive tract, most commonly the ileum, colon and perianal region. This disease is characterized by erosions, ulcers, inflammatory thickening of the intestinal wall and noncaseating granulomas.Assessment of the extent and activity of Crohn's disease presents difficulties, often requiring a combination of clinical, biochemical, endoscopic, histological and imaging studies. Computerized tomography (CT) and conventional contrast study play an important role in evaluating such patients. Magnetic resonance imaging (MR) has proved to be an advantageous technique due to the absence of ionizing radiation and its excellent detection capability of the various findings of this entity such as mural thickening, fistula, abscess , mesenteric vascularity and lymphadenopathy. MR is also important for its ability to depict extraenteric regions, less accessible to endoscopic techniques.The objective of this study is to demonstrate the different manifestations of Crohn's disease detected by MR and its value to confirm the diagnosis, detect complications and characterize signs of activity.MR-Enterographic studies will be performed in patients referred from specialized clinic . Patients will undergo different sequences of protocol in 1.5T-equipment . All exams will be evaluated by the authors that will classify the imaging findings and other informations including age, sex and clinical manifestations.All obtained informations will be analyzed ,listed and grouped for comparative study and correlation of images.

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