Molecular characterization of the gene encoding TCTP (Translationally Controlled Tumor Protein) in tomato (Solanum lycopersicum cv Santa Clara)

• Grant number: 11/17462-1
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: December 01, 2011
• End date: November 30, 2012
• Field of knowledge: Biological Sciences - Genetics - Plant Genetics
• Principal Investigator: Ivan de Godoy Maia
• Grantee: Laura Migliorini de Araujo
• Host Institution: Instituto de Biociências (IBB). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil

Abstract

The gene encoding TCTP (Translationally Controlled Tumour Protein) is present in all eukaryotes and its product is involved in different cellular processes. Although well characterized in mammals, there are few data available in the literature related to the analysis of this protein in plants. Thus, the aim of this work is the characterization of the gene encoding TCTP in plants, taking the tomato plant (Solanum lycopersicum cv. Santa Clara) as the experimental model. The objective of this project is to investigate the expression of this gene in different organs/tissues along the plant development as well to analyze the impact of overexpression of tomato TCTP in transgenic tobacco. Based on studies showing that, in some species, the control of the synthesis of homologous proteins to TCTP does not occur only at the transcriptional level, the aim is also to correlate gene expression with the accumulation of the protein in such organs/tissues.(AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE CARVALHO, MARCIO; ACENCIO, MARCIO LUIS; NUNES LAITZ, ALESSANDRA VASCONCELLOS; DE ARAUJO, LAURA MIGLIORINI; CAMPOS ARCURI, MARIANA DE LARA; DO NASCIMENTO, LEANDRO COSTA; MAIA, IVAN G.. Impacts of the overexpression of a tomato translationally controlled tumor protein (TCTP) in tobacco revealed by phenotypic and transcriptomic analysis. Plant Cell Reports, v. 36, n. 6, p. 887-900, JUN 2017. (11/17462-1, 14/03241-1, 11/10309-3)