Cyclosporin A (CsA) is an immunosupressive drug, widely used against auto-immune diseases and for treatment after organ transplants. However, its use causes various collateral effects, including nephrotoxicity and hepatotoxicity. It also caused damage to the male reproductive system and reduction of testorone production. Heteropterys aphrodisiaca is a plant typical of the Cerrado region of Brazil, popularly known as an aphrodisiac and a stimulating tonic. The infusion of roots of this plant has been observed to atenuate the damage caused by CsA in the testicles, ventral prostate and liver. The objective of this study is to confirm whether the infusion of H. aphrodisiaca roots reduces the collateral effects on the testicles and ventral prostate after cylosporine use during 21 days. This will be evaluated by morphologic, morphometric and steriological analysis of testicular and prostatic tissue.
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