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Production of ligninolytic enzymes, glyoxal oxidases and proteases by marine fungi

Grant number: 12/00085-3
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): May 01, 2012
Effective date (End): April 30, 2013
Field of knowledge:Biological Sciences - Microbiology - Applied Microbiology
Principal Investigator:Lara Durães Sette
Grantee:Ramon Peres Brexó
Host Institution: Instituto de Biociências (IB). Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Rio Claro , SP, Brazil
Associated research grant:10/50190-2 - Investigation of metabolic and biotechnological potential of marine organisms in bioremediation processes and for the production of substances with anti-viral, anti-inflammatory and anti-Leishmania activities (Marine Biodiversity), AP.BTA.TEM


Marine-derived filamentous fungi are promising resources for biotechnological exploitation since this habitat covers more than 70% of the surface of the planet and marine mycology is a recent science where little is known about the potential biodiversity and genetic resources of these organisms. Currently, the analysis and application of the catabolic capability of microorganisms are promising for the control and destruction of organic contaminants, besides having great applicability in important industrial processes. Given these trends, this project aims to analyze the production of ligninolytic enzymes lignin peroxidase (LiP) and manganese peroxidase (MnP), and glyoxal oxidase (GLOX), and assess the production of proteases. These enzymes have potential biotechnological applications in various socio-economic sectors such as bioremediation of effluents from the textile industry, the degradation of nitrated explosives, pesticides, polycyclic aromatic hydrocarbons, and polymers, as well as pulp and paper industry, food, leather, pharmaceutical, cosmetics, among others. It is worth mentioning that this project is associated with the FAPESP Thematic 2010/50190-2 "Investigation of the biotechnological potential and metabolic processes from marine organisms for bioremediation and production of anti-viral, anti-Leishmania and anti-inflammatory substances."(AU)

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