Production of ligninolytic enzymes, glyoxal oxidases and proteases by marine fungi.

• Grant number: 12/00085-3
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: May 01, 2012
• End date: April 30, 2013
• Field of knowledge: Biological Sciences - Microbiology - Applied Microbiology
• Principal Investigator: Lara Durães Sette
• Grantee: Ramon Peres Brexó
• Host Institution: Instituto de Biociências (IB). Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Rio Claro , SP, Brazil
• Associated research grant: 10/50190-2 - Investigation of metabolic and biotechnological potential of marine organisms in bioremediation processes and for the production of substances with anti-viral, anti-inflammatory and anti-Leishmania activities (Marine Biodiversity), AP.BTA.TEM

Abstract

Marine-derived filamentous fungi are promising resources for biotechnological exploitation, since this habitat covers more than 70% of the surface of the planet and marine mycology is a recent science where little is known about the potential biodiversity and genetic resources from these organisms. Currently, analysis and application of catabolic capability of microorganisms is promising for the control and destruction of organic contaminants, besides having great applicability in important industrial processes. Given these trends, this project aims to analyze the production of ligninolytic enzymes lignin peroxidase (LiP) and manganese peroxidase (MnP) and glyoxal oxidase (GLOX), and assess the production of proteases. These enzymes have potential biotechnological application in various socio-economic sectors such as bioremediation of effluents from textile industry, the degradation of nitrated explosives, pesticides, polycyclic aromatic hydrocarbons and polymers, as well as pulp and paper industry, food, leather, pharmaceutical, cosmetics, among others. It is worth to mention that this project is associated with the FAPESP Thematic 2010/50190-2 "Investigation of the biotechnological potential and metabolic processes from marine organisms for bioremediation and production of anti-viral, anti-Leishmania and anti-inflammatory substances."