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Histopathological and immunohistochemical evaluation of health aspects of humpback whales (Megaptera novaeangliae) with emphasis on the research of Morbillivirus sp

Grant number: 12/00021-5
Support Opportunities:Scholarships abroad - Research Internship - Doctorate (Direct)
Effective date (Start): May 01, 2012
Effective date (End): July 31, 2012
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Pathology
Principal Investigator:Jose Luiz Catao Dias
Grantee:Kátia Regina Groch
Supervisor: Antonio J. Fernández Rodriguez
Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Research place: Universidad de Las Palmas de Gran Canaria (ULPGC), Spain  


This research proposal aims to investigate the pathological changes in tissues of humpback whales (Megaptera novaeangliae), identify possible diseases and evaluate the occurrence of Morbillivirus infection in selected tissues using immunohistopathological techniques. We intend to review histopathological material selected from 250 samples of skin from whales, as well as to review histopathological slides of 91 samples obtained during necropsy examination of eight humpback whales that stranded along the Brazilian coast. Suggestive cases of infection by Morbillivirus sp. will be analyzed applying immunohistochemical techniques. Special tissue staining methods, as well as immunohistopathological techniques for research of other pathogenic organisms, may be used when appropriate and feasible. It is expected that the results of this research will bring an important contribution to the development of the current doctoral thesis, especially in relation to diagnostic methods, and interpretation of pathological changes in humpback whales. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
GROCH, KATIA REGINA; DIAZ-DELGADO, JOSUE; MARCONDES, MILTON C. C.; COLOSIO, ADRIANA CASTALDO; SANTOS-NETO, ELITIERI B.; CARVALHO, VITOR LUZ; BOOS, GISELA SILVA; OLIVEIRA DE MEIRELLES, ANA CAROLINA; DA CUNHA RAMOSE, HERNANI GOMES; GUIMARAES, JULIANA PLACIDO; et al. Pathology and causes of death in stranded humpback whales (Megaptera novaeangliae) from Brazil. PLoS One, v. 13, n. 5, . (15/05043-5, 15/00735-6, 12/00021-5, 11/08357-0, 14/24932-2)
GROCH, KATIA R.; MARCONDES, MILTON C. C.; COLOSIO, ADRIANA C.; CATAO-DIAS, JOSE LUIZ. Skeletal abnormalities in humpback whales Megaptera novaeangliae stranded in the Brazilian breeding ground. DISEASES OF AQUATIC ORGANISMS, v. 101, n. 2, p. 145-158, . (12/00021-5, 11/08357-0)

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