Evaluation of the frequency, clinical presentation and evolution of non-melanoma skin cancer in renal transplant receptors.

• Grant number: 12/12271-6
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: September 01, 2012
• End date: August 31, 2013
• Field of knowledge: Health Sciences - Medicine
• Principal Investigator: Jane Tomimori
• Grantee: Marina Zoega Hayashida
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil

Abstract

The non-melanoma skin cancer (NMSC) is the most common tumor following renal transplant corresponding to almost 50% of the malignancies that affect this population. Many agents work together to increase the risk of skin cancer. Among them are included the use of immunosuppressive drugs, sunlight exposure, viral infection, individual genetic background, skin type and age below. Some studies have shown the prevalence of NMSC in renal transplant recipients (RTR) in some scenarios, but not yet settled fully the clinical characteristics and evolution of these patients. Thus, the main objectives of this study are to evaluate the frequency, characterize the clinical development of cancer and non-melanoma skin in RTR patients who attended outpatient dermatological consultation in the Immunocompromised Transplant Group, Department of Dermatology, UNIFESP-EPM from January 2004 to December 2009. To achieve the objectives mentioned, the methodology adopted is qualitative and quantitative, and will analyze the historical RTR patients with a history of NMSC. The analysis will be made from the assessment of demographic parameters and related to the transplant and skin cancer.