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High blood pressure and aggregation of risk factors in adolescents: a multicenter study

Grant number: 11/20662-2
Support type:Scholarships abroad - Research Internship - Doctorate
Effective date (Start): March 01, 2012
Effective date (End): February 28, 2013
Field of knowledge:Health Sciences - Medicine - Maternal and Child Health
Principal researcher:Heraclito Barbosa de Carvalho
Grantee:Augusto César Ferreira de Moraes
Supervisor abroad: Luis Alberto Moreno Aznar
Home Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Research place: Universidad de Zaragoza, Spain  
Associated to the scholarship:11/11137-1 - High blood pressure and aggregation of risk factors in adolescents: a multicenter study, BP.DR

Abstract

The objectives are: (i) estimate the prevalence of high blood pressure (HBP) in adolescents aged 13-18 years from ten countries; (ii) to analyze the sociodemographic and behavioral factors associated with this outcome. Methods: This project is a multicenter collaborative study conducted by Brazilian and Europe researchers with standardized procedures for sampling, recruitment and data collection. The school-based survey were conducted with probability sampling in high school students from Brazil and nine European countries. Brazilian data are from the research "Cardiovascular risk factors: biological and behavioral indicators" and the data from European countries are "Healthy lifestyle in Europe by nutrition in adolescence cross-sectional study". Outcome for this project is HBP, diagnosed by measuring levels of systolic and diastolic pressure by validated method for this population. The independent variables will be examined are: country, age, type of school, parental education, parental employment status, level of physical activity, sedentary behavior, eating habits, regular consumption of tobacco and drinking alcohol and nutritional status. To analyze the magnitude of associations between exposures and the outcome will be applied to Poisson regression with robust variance, through a hierarchical conceptual model will be developed. (AU)

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Scientific publications (15)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
REY-LOPEZ, J. P.; BEL-SERRAT, S.; SANTALIESTRA-PASIAS, A.; DE MORAES, A. C.; VICENTE-RODRIGUEZ, G.; RUIZ, J. R.; ARTERO, E. G.; MARTINEZ-GOMEZ, D.; GOTTRAND, F.; DE HENAUW, S.; et al. Sedentary behaviour and clustered metabolic risk in adolescents: The HELENA study. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, v. 23, n. 10, p. 1017-1024, . (11/20662-2, 11/11137-1)
RENDO-URTEAGA, TARA; CESAR FERREIRA DE MORAES, AUGUSTO; SADALLA COLLESE, TATIANA; MANIOS, YANNIS; HAGSTROMER, MARIA; SJOSTROM, MICHAEL; KAFATOS, ANTHONY; WIDHALM, KURT; VANHELST, JEREMY; MARCOS, ASCENSION; et al. The combined effect of physical activity and sedentary behaviors on a clustered cardio-metabolic risk score: The Helena study. INTERNATIONAL JOURNAL OF CARDIOLOGY, v. 186, p. 186-195, . (11/20662-2, 11/11137-1)
FERREIRA DE MORAES, AUGUSTO CESAR; CASSENOTE, ALEX JONES FLORES; LECLERCQ, CATHERINE; DALLONGEVILLE, JEAN; ANDROUTSOS, ODYSSEAS; TOEROEK, KATALIN; GONZALEZ-GROSS, MARCELA; WIDHALM, KURT; KAFATOS, ANTHONY; CARVALHO, HERACLITO BARBOSA; et al. Resting Heart Rate Is Not a Good Predictor of a Clustered Cardiovascular Risk Score in Adolescents: The HELENA Study. PLoS One, v. 10, n. 5, . (14/13367-2, 11/20662-2, 11/11137-1)
FERREIRA DE MORAES, AUGUSTO CESAR; MIGUEL FERNANDEZ-ALVIRA, JUAN; CARVALHO, HERACLITO BARBOSA; MEIRHAEGHE, ALINE; DALLONGEVILLE, JEAN; KAFATOS, ANTHONY; MARCOS, ASCENSION; MOLNAR, DENES; MANIOS, YANNIS; RUIZ, JONATAN R.; et al. Physical Activity Modifies the Associations between Genetic Variants and Blood Pressure in European Adolescents. JOURNAL OF PEDIATRICS, v. 165, n. 5, p. 1046-U237, . (11/20662-2, 11/11137-1)
FERREIRA DE MORAES, AUGUSTO CESAR; LACERDA, MARIA BEATRIZ; MORENO, LUIS A.; HORTA, BERNARDO L.; CARVALHO, HERACLITO BARBOSA. Prevalence of High Blood Pressure in 122,053 Adolescents: A Systematic Review and Meta-Regression. MEDICINE, v. 93, n. 27, . (11/20662-2, 11/17211-9, 11/11137-1)
REY-LOPEZ, J. P.; DE CARVALHO, H. B.; DE MORAES, A. C. F.; RUIZ, J. R.; SJOSTROM, M.; MARCOS, A.; POLITO, A.; GOTTRAND, F.; MANIOS, Y.; KAFATOS, A.; et al. Sleep time and cardiovascular risk factors in adolescents: The HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence) study. Sleep Medicine, v. 15, n. 1, p. 104-110, . (11/20662-2, 12/05723-8, 11/11137-1)
GRACIA-MARCO, LUIS; MORENO, LUIS A.; RUIZ, JONATAN R.; ORTEGA, FRANCISCO B.; FERREIRA DE MORAES, AUGUSTO CESAR; GOTTRAND, FREDERIC; ROCCALDO, ROMANIA; MARCOS, ASCENSION; GOMEZ-MARTINEZ, SONIA; DALLONGEVILLE, JEAN; et al. Body Composition Indices and Single and Clustered Cardiovascular Disease Risk Factors in Adolescents: Providing Clinical-Based Cut-Points. PROGRESS IN CARDIOVASCULAR DISEASES, v. 58, n. 5, p. 555-564, . (11/20662-2, 11/11137-1)
FERREIRA DE MORAES, AUGUSTO CESAR; CARVALHO, HERACLITO BARBOSA; GOMEZ-MARTINEZ, SONIA; ANDROUTSOS, ODYSSEAS; JIMENEZ-PAVON, DAVID; SJOSTROM, MICHAEL; KAFATOS, ANTHONY; WIDHALM, KURT; CANADA, DAVID; MARTIN-MATILLAS, MIGUEL; et al. Family socioeconomic factors are negatively associated with blood pressure in European boys, but not girls, and Brazilian adolescents: Results from two observational studies. BLOOD PRESSURE, v. 24, n. 4, p. 250-257, . (11/11137-1, 11/20662-2)
FERREIRA DE MORAES, AUGUSTO CESAR; GRACIA-MARCO, LUIS; IGLESIA, IRIS; GONZALEZ-GROSS, MARCELA; BREIDENASSEL, CHRISTINA; FERRARI, MARIKA; MOLNAR, DENES; GOMEZ-MARTINEZ, SONIA; ANDROUTSOS, ODYSSEAS; KAFATOS, ANTHONY; et al. Vitamins and iron blood biomarkers are associated with blood pressure levels in European adolescents. The HELENA study. NUTRITION, v. 30, n. 11-12, p. 1294-1300, . (11/20662-2, 11/11137-1)
FERREIRA DE MORAES, AUGUSTO CESAR; CARVALHO, HERACLITO BARBOSA; SIANI, ALFONSO; BARBA, GIANVINCENZO; VEIDEBAUM, TOOMAS; TORNARITIS, MICHAEL; MOLNAR, DENES; AHRENS, WOLFGANG; WIRSIK, NORMAN; DE HENAUW, STEFAAN; et al. Incidence of high blood pressure in children - Effects of physical activity and sedentary behaviors: The IDEFICS study High blood pressure, lifestyle and children. INTERNATIONAL JOURNAL OF CARDIOLOGY, v. 180, p. 165-170, . (11/20662-2, 11/11137-1)
CESAR FERREIRA DE MORAES, AUGUSTO; BEL-SERRAT, SILVIA; MANIOS, YANNIS; MOLNAR, DENES; KAFATOS, ANTHONY; CUENCA-GARCIA, MAGDALENA; HUYBRECHTS, INGE; SETTE, STEFANIA; WIDHALM, KURT; STEHLE, PETER; et al. Dietary protein and amino acids intake and its relationship with blood pressure in adolescents: the HELENA STUDY. EUROPEAN JOURNAL OF PUBLIC HEALTH, v. 25, n. 3, p. 450-456, . (11/20662-2, 11/11137-1)
FERREIRA DE MORAES, AUGUSTO CESAR; CARVALHO, HERACLITO BARBOSA; REY-LOPEZ, JUAN PABLO; GRACIA-MARCO, LUIS; BEGHIN, LAURENT; KAFATOS, ANTHONY; JIMENEZ-PAVON, DAVID; MOLNAR, DENES; DE HENAUW, STEFAAN; MANIOS, YANNIS; et al. Independent and Combined Effects of Physical Activity and Sedentary Behavior on Blood Pressure in Adolescents: Gender Differences in Two Cross-Sectional Studies. PLoS One, v. 8, n. 5, . (11/20662-2, 11/11137-1)
LIN, YI; MOURATIDOU, THEODORA; VEREECKEN, CARINE; KERSTING, MATHILDE; BOLCA, SELIN; DE MORAES, AUGUSTO CESAR F.; CUENCA-GARCIA, MAGDALENA; MORENO, LUIS A.; GONZALEZ-GROSS, MARCELA; VALTUENA, JARA; et al. Dietary animal and plant protein intakes and their associations with obesity and cardio-metabolic indicators in European adolescents: the HELENA cross-sectional study. NUTRITION JOURNAL, v. 14, . (11/20662-2, 11/11137-1)
FERRARI, M.; CUENCA-GARCIA, M.; VALTUENA, J.; MORENO, L. A.; CENSI, L.; GONZALEZ-GROSS, M.; ANDROUTSOS, O.; GILBERT, C. C.; HUYBRECHTS, I.; DALLONGEVILLE, J.; et al. Inflammation profile in overweight/obese adolescents in Europe: an analysis in relation to iron status. European Journal of Clinical Nutrition, v. 69, n. 2, p. 247-255, . (11/20662-2, 11/11137-1)
DE MORAES, A. C. F.; MUSSO, C.; GRAFFIGNA, M. N.; SOUTELO, J.; MIGLIANO, M.; CARVALHO, H. B.; BERG, G.. Prevalence of cardiovascular risk factors among Latin American adolescents: a multilevel analysis. JOURNAL OF HUMAN HYPERTENSION, v. 28, n. 3, p. 206-209, . (11/11137-1, 11/20662-2)

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