|Support type:||Scholarships in Brazil - Doctorate|
|Effective date (Start):||November 01, 2012|
|Effective date (End):||October 31, 2015|
|Field of knowledge:||Health Sciences - Medicine|
|Principal researcher:||Alan Stewart Hazell|
|Grantee:||Vinícius Rodrigues Silva|
|Home Institution:||Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil|
The present study aimed primarily to see if there are changes on the expression of glutamate receptors and their contribution to increasing the extracellular concentration of glutamate and its effect on neurological dysfunction in mice with acute liver failure induced by Azoxymethane, the second objective is to determine this the influence of glutamate depolarization of nerve cells in mice with severe acute exacerbated by varying the ammonia concentration is a factor that influences the depolarization of nerve cells, causing a greater disease in dysfunction.