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Preparation and characterization of solid lipid nanoparticles as a carrier system for both atrazine and simazine herbicides aiming future agricultural applications

Grant number: 12/20076-9
Support type:Scholarships in Brazil - Master
Effective date (Start): March 01, 2013
Effective date (End): February 28, 2015
Field of knowledge:Biological Sciences - Biochemistry - Chemistry of Macromolecules
Principal researcher:Leonardo Fernandes Fraceto
Grantee:Jhones Luiz de Oliveira
Home Institution: Universidade Estadual Paulista (UNESP). Campus Experimental de Sorocaba. Sorocaba , SP, Brazil
Associated research grant:09/00294-9 - Micro/nanostructured release systems for triazinic herbicides for agricultural application, AP.JP


In order to increase the amount and quality of agricultural products, today the agricultural production system uses high-tech equipment and a large amount of pesticides to minimize the impacts of pests and thereby increase agricultural productivity. Although they have an important role in agricultural production, agricultural pesticides cause a major environmental impact, as they are a major contaminant of water resources, being found in surface water bodies and underground. Due to the large agricultural production, Brazil has become a major consumer of pesticides, including herbicides are. The triazine herbicides atrazine and simazine as are widely used in plantations of sugar cane and corn, with Brazil being one of the leaders in cultivation. Taking into account all these factors, there has been much studied in order to minimize the damage caused by these herbicides example, the development of nanostructured systems for modified release, which can enable an increase in performance / efficiency of these products, as well as minimize environmental impacts and human health. The objective of this master's project is to develop a modified release system, based on solid lipid nanoparticles for the encapsulation of two joint triazine herbicides, atrazine and simazine in order to minimize the impacts caused by him and also to increase the efficiency herbicide . The importance of this project is linked to the large market of herbicides in Brazil and thus, research in the area of crop protection technology that can add value and minimize environmental impacts are extremely important to the agricultural production sector in our country, thus bringing great benefits to the industry, environment and society.

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DE OLIVEIRA, JHONES LUIZ; RAMOS CAMPOS, ESTEFANIA VANGELIE; GONCALVES DA SILVA, CAMILA MORAIS; PASQUOTO, TATIANE; LIMA, RENATA; FRACETO, LEONARDO FERNANDES. Solid Lipid Nanoparticles Co-loaded with Simazine and Atrazine: Preparation, Characterization, and Evaluation of Herbicidal Activity. Journal of Agricultural and Food Chemistry, v. 63, n. 2, p. 422-432, JAN 21 2015. Web of Science Citations: 32.
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
OLIVEIRA, Jhones Luiz de. Preparo e caracterização de nanopartículas lipídicas sólidas como sistema carreador conjunto para os herbicidas atrazina e simazina visando futuras aplicações em agricultura. 2015. Master's Dissertation - Universidade Estadual Paulista (Unesp). Instituto de Ciência e Tecnologia. Sorocaba Sorocaba.

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