Scholarship 12/23810-5 - Síntese orgânica, Reação de Diels-Alder - BV FAPESP
Advanced search
Start date
Betweenand

Studies in asymmetric hetero Diels-Alder reaction

Grant number: 12/23810-5
Support Opportunities:Scholarships abroad - Research Internship - Scientific Initiation
Start date until: April 01, 2013
End date until: July 31, 2013
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Organic Chemistry
Principal Investigator:Ronaldo Aloise Pilli
Grantee:Luiz Fernando Toneto Novaes
Supervisor: Karl Gademann
Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Institution abroad: University of Basel, Switzerland  
Associated to the scholarship:12/09254-2 - Synthesis of the tarchonanthuslactone, analogues and evaluation of anticancer and antidiabetic activity, BP.IC

Abstract

The present project aims to study the Hetero Diels-Alder reaction (HDA), as a tool to construct alfa, beta-unsaturated delta-lactones, an important structural moiety present in natural products such as goniothalamin and fostriecin which display biological activity against cancer. We plan to study two asymmetric HDA methods, one based on the Jacobsen's catalyst, the other using Lewis acids and chiral beta-alkoxy-aldehydes to create new asymmetric centers. (AU)

News published in Agência FAPESP Newsletter about the scholarship:
More itemsLess items
Articles published in other media outlets ( ):
More itemsLess items
VEICULO: TITULO (DATA)
VEICULO: TITULO (DATA)

Please report errors in scientific publications list using this form.