|Support type:||Scholarships in Brazil - Doctorate|
|Effective date (Start):||April 01, 2013|
|Effective date (End):||February 28, 2017|
|Field of knowledge:||Physical Sciences and Mathematics - Chemistry - Analytical Chemistry|
|Principal researcher:||José Anchieta Gomes Neto|
|Grantee:||Felipe Manfroi Fortunato|
|Home Institution:||Instituto de Química (IQ). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil|
A new calibration method in analytical chemistry combining the standard addition and internal standardization methods is proposed in this Doctoral Thesis. The internal standard addition using gradient flow analysis is a novel method and benefits in the field of quantitative chemical analysis are: a) correct for matrix or transport effects, and fluctuations due to changes in sample size, instrumental parameters; b) minimal manipulation of sample and standard solutions, c) reduction of reagent consumption and analysis time; d) minimization of contamination and loss of analyte by employing dynamical systems in pipelines; e) analyst exposure (or contact) to numerous chemicals is reduced. The benefits of this proposal are clear and will be demonstrated by using two spectroscopic techniques: high-resolution continuum source flame atomic absorption spectrometry (in the determination of Ca, K, Mg and Na in biodiesel and urine) and Raman spectroscopy (in the determination of uric acid, creatinine and urea in urine; benzene, toluene, ethylbenzene and xylenes - BTEX - in gasoline, methanol in gasoline, ethanol and biodiesel, biodiesel in diesel).