Electrolyte-gated organic field-effect transistors (EGOFETs) for fabrication of new biosensors

• Grant number: 13/03857-0
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate
• Effective date (Start): June 01, 2013
• Effective date (End): May 31, 2014
• Field of knowledge: Physical Sciences and Mathematics - Physics - Condensed Matter Physics
• Principal Investigator: Marystela Ferreira
• Grantee: Rafael Furlan de Oliveira
• Supervisor: Fabio Biscarini
• Host Institution: Centro de Ciências e Tecnologias para a Sustentabilidade (CCTS). Universidade Federal de São Carlos (UFSCAR). Sorocaba , SP, Brazil
• Research place: Università degli Studi di Modena e Reggio Emilia, Modena (UNIMORE), Italy
• Associated to the scholarship: 11/00229-2 - "Development of Organic Electronic Devices and their Application as Sensors in Aqueous Medium", BP.DR

Abstract

Electrolyte-gated organic field-effect transistors (EGOFETs) are ultra-sensitive devices that have been attracting much attention in aqueous-medium sensing due to their low-operational voltages and intrinsic signal amplification. EGOFETs are also suitable platforms either for point-of-care tests and real-time monitoring of many analytes of medical interest. Here, we propose the developing of EGOFETs able to detect different neurotransmitters and cytokines, key biomarkers for diagnostics and/or prognostics of spinal cord injury (SCI). The real-time monitoring of such species during a transient process is a crucial issue on medical applications for a correct healing of the injured site. The development of EGOFET biosensors for such purpose can contribute to the acquisition of the knowledge and the technology to improve studies on SCI recovery. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

CASALINI, STEFANO; DUMITRU, ANDRA C.; LEONARDI, FRANCESCA; BORTOLOTTI, CARLO A.; HERRUZO, ELENA T.; CAMPANA, ALESSANDRA; DE OLIVEIRA, RAFAEL F.; CRAMER, TOBIAS; GARCIA, RICARDO; BISCARINI, FABIO. Multiscale Sensing of Antibody - Antigen Interactions by Organic Transistors and Single-Molecule Force Spectroscopy. ACS NANO, v. 9, n. 5, p. 5051-5062, MAY 2015. (13/03857-0)

DE OLIVEIRA, RAFAEL FURLAN; CASALINI, STEFANO; CRAMER, TOBIAS; LEONARDI, FRANCESCA; FERREIRA, MARYSTELA; VINCIGUERRA, VINCENZO; CASUSCELLI, VALERIA; ALVES, NERI; MURGIA, MAURO; OCCHIPINTI, LUIGI; et al. Water-gated organic transistors on polyethylene naphthalate films. FLEXIBLE AND PRINTED ELECTRONICS, v. 1, n. 2, JUN 1 2016. (11/00229-2, 13/03857-0)