Scholarship 13/07315-7 - Fertilidade animal, Seleção genética - BV FAPESP
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Genomic selection for improved fertility of dairy cows with emphasis on cyclicity and pregnancy

Grant number: 13/07315-7
Support Opportunities:Scholarships abroad - Research Internship - Doctorate (Direct)
Start date until: August 01, 2013
End date until: June 30, 2014
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Reproduction
Principal Investigator:Mario Binelli
Grantee:Roney dos Santos Ramos
Supervisor: Pablo J. Pinedo
Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Institution abroad: Texas A&M University, United States  
Associated to the scholarship:12/23532-5 - Effect of the periovulatory endocrine milieu on polyamines synthesis pathway in endometrium during the first week of the estrous cycle in cattle, BP.DD

Abstract

Development and implementation of genetic selection of dairy cattle has been the major method to improve productivity per animal; however, selection has been focused on production traits and only more recently reproduction and health traits. Moreover genetic selection for fertility traits has been slow because of use of indirect methods that are influenced more by the environment than controlled by genetics. The overall objective of this integrated proposal that includes research, extension, and education components is to make use of advanced genomic technologies to improve the efficiency of dairy animals for fertility traits through genomic selection. To achieve this objective, our aim is to identify single nucleotide polymorphisms and haplotypes associated with direct measures of fertility in dairy cow populations (namely resumption of postpartum ovulation, detection of estrus, pregnancy, pregnancy loss, and uterine health). It is our central hypothesis that reproduction in dairy cows is controlled, to some extent, by genetic components, and sufficient genetic variation for fertility traits exists in dairy cow populations to implement efficient selection programs. The long-term goal of this integrated multistate project is to provide new resources for the understanding, and consequently, the improvement of dairy cattle fertility via identification of molecular markers significantly associated with reproductive efficiency. Our project will result in tools for selection of dairy cattle populations for improved fertility concurrent with increases in yields of milk and milk components. (AU)

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