Influence of carbon nanostructures on the viability, formation and elongation of dendrites in cortical neuron cultures

• Grant number: 13/07961-6
• Support Opportunities: Scholarships abroad - Research Internship - Master's degree
• Start date: August 15, 2013
• End date: February 14, 2014
• Field of knowledge: Biological Sciences - Morphology - Cytology and Cell Biology
• Principal Investigator: Alexandre Leite Rodrigues de Oliveira
• Grantee: Kyl Assaf
• Supervisor: Charles Patrick Case
• Host Institution: Instituto de Biologia (IB). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Institution abroad: University of Bristol, England
• Associated to the scholarship: 12/08251-0 - Repair of peripheral nerves with the use of PCL and carbon nanostructures., BP.MS

Abstract

Carbon nanostructures have been shown to have a wide range of applications in several fields. However, characterization seems to be a key factor in order to make data comparable. The nanostructures of carbon are indeed one of the most promising for enhancing neuronal regeneration and include CNTs, graphene sheets and carbon nanofibers. The present study will analyze the eventual cytotoxic effects of nanoparticles of carbon in neuronal cultures exposed to different concentrations of such materials (0,1, 1,0 e 10 ug/ml. (AU)