Asymmetry in the Parkinson Disease: effects on walking and posture

• Grant number: 12/24040-9
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: May 01, 2013
• End date: March 31, 2014
• Field of knowledge: Health Sciences - Physical Education
• Principal Investigator: Lilian Teresa Bucken Gobbi
• Grantee: Fabio Augusto Barbieri
• Host Institution: Instituto de Biociências (IB). Universidade Estadual Paulista (UNESP). Campus de Rio Claro. Rio Claro , SP, Brazil

Abstract

The most patients with Parkinson's disease (PD) shows unilateral motor impairment. However, the motor control related to asymmetry on walking and postural control is not well known. The general aim of this study will be to analyze the asymmetry on walking, with and without environmental demands, and posture, according to the effect of medication, of the patients with PD in early and moderate stages of the disease. To answer the questions of the project, two studies will be developed, which will address the asymmetry on walking with and without auditory cue and postural control in different static positions. Thirty patients with PD, who will be to distribute in two groups according to stage of the disease, and 15 neurologically healthy individuals will participate in the study. The participants will perform clinical evaluation: stage of the disease, PD degree of involvement, and cognitive conditions; motor evaluation: coordination, strength and range of motion; walking evaluation: it will be assessed spatiotemporal and kinetic parameters, analyzing the asymmetry between the sides during the tasks; posture evaluation: it will be evaluated postural control in bipedal support, tandem position, and unipedal support, comparing the asymmetry between the limbs. The PD patients will perform the evaluations in "ON" and "OFF" state of the medication. The clinical data will be compared using nonparametric tests. The data related to motor tests, walking and postural parameters will be compared through MANOVAs according independent variables of the study.

Scientific publications

(5)

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

PENEDO, TIAGO; KALVA-FILHO, CARLOS AUGUSTO; CURSIOL, JONATAS AUGUSTO; FARIA, MURILO HENRIQUE; COELHO, DANIEL BOARI; BARBIERI, FABIO AUGUSTO. Spatial-temporal parameters during unobstructed walking in people with Parkinson's disease and healthy older people: a public data set. FRONTIERS IN AGING NEUROSCIENCE, v. 16, p. 7-pg., 2024-03-28. (20/01250-4, 22/16112-1, 18/03448-6, 14/20549-0, 17/19516-8, 19/24752-8, 15/15928-4, 22/02971-2, 12/24040-9, 21/09690-6)

BERETTA, VICTOR SPIANDOR; BARBIERI, FABIO AUGUSTO; ORCIOLI-SILVA, DIEGO; ROCHA DOS SANTOS, PAULO CEZAR; SIMIELI, LUCAS; VITORIO, RODRIGO; BUCKEN GOBBI, LILIAN TERESA. Can Postural Control Asymmetry Predict Falls in People With Parkinson's Disease?. MOTOR CONTROL, v. 22, n. 4, p. 449-461, OCT 2018. (13/00925-4, 10/07040-0, 12/24040-9)

CURSIOL, JONATAS AUGUSTO; DOS SANTOS, PAULO CEZAR ROCHA; BERETTA, VICTOR SPIANDOR; ORCIOLI-SILVA, DIEGO; SIMIELI, LUCAS; SCHLENSTEDT, CHRISTIAN; COELHO, DANIEL BOARI; BARBIERI, FABIO AUGUSTO. Rhythmic auditory cues improve gait asymmetry during unobstructed walking in people with Parkinson's disease but have no effect on obstacle avoidance - AsymmGait-Parkinson study. FRONTIERS IN AGING NEUROSCIENCE, v. 17, p. 11-pg., 2025-02-27. (22/02971-2, 12/24040-9)

BARBIERI, FABIO A.; POLASTRI, PAULA F.; BAPTISTA, ANDRE M.; LIRANI-SILVA, ELLEN; SIMIELI, LUCAS; ORCIOLI-SILVA, DIEGO; BERETTA, VICTOR S.; GOBBI, LILIAN T. B.. Effects of disease severity and medication state on postural control asymmetry during challenging postural tasks in individuals with Parkinson's disease. HUMAN MOVEMENT SCIENCE, v. 46, p. 96-103, APR 2016. (13/00925-4, 12/24040-9)

BARBIERI, FABIO AUGUSTO; CARPENTER, MARK; BERETTA, VICTOR SPIANDOR; ORCIOLI-SILVA, DIEGO; SIMIELI, LUCAS; VITORIO, RODRIGO; BUCKEN GOBBI, LILIAN TERESA. Postural control, falls and Parkinson's disease: Are fallers more asymmetric than non-fallers?. HUMAN MOVEMENT SCIENCE, v. 63, p. 129-137, FEB 2019. (13/00925-4, 12/24040-9)