The influence of genetics polymorphisms and mutations in the development of hereditary prostate Cancer

• Grant number: 13/01488-7
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: May 01, 2013
• End date: April 30, 2014
• Field of knowledge: Health Sciences - Medicine - Surgery
• Principal Investigator: Sabrina Thalita dos Reis Faria
• Grantee: Daniela Cristina Janolli Sanchez
• Host Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The purpose of this study is to analyze the profile of Single Nucleotide Polymorphisms (SNP) between patients with and without prostate cancer with a history of hereditary disease and control group. The first group will provide patients with prostate cancer, members of families with two or more relatives affected by the disease and at least one first degree, or a relative who has been diagnosed before 55 years of age, the second will consist of patients healthy without prostate cancer, members of families with two or more relatives affected by the disease and at least one first-degree and the control group will consist of patients with CP with no family history. (AU)