Serum evoluatin of molonyldialdeido and carotnoides in obsee womem

• Grant number: 13/02614-6
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: July 01, 2013
• End date: December 31, 2013
• Field of knowledge: Health Sciences - Nutrition - Nutrition Biochemistry
• Principal Investigator: Camila Renata Corrêa
• Grantee: Claudia Diniz Lopes de Oliveira
• Host Institution: Faculdade de Medicina (FMB). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil

Abstract

The prevalence of obesity has increased during the last two decades, this increase has been attributed to changes in the dietary habit where prevails the increase of fats and sugars. It is clear that obesity is a risk factor for cardiovascular disease and insulin resistance and oxidative stress favor this context. This situation can be either by a deficiency in the consumption of foods rich in antioxidants as well as the use of antioxidants by the body in an attempt to combat free radicals generated in excess in obesity conditions. The aim of the study is to investigate the serum levels of carotenoids and malondialdehyde indicator of lipid peroxidation in obese women. Will be evaluated 96 obese women followed in the clinic of Endocrinology, Department of Internal Medicine of the Hospital of the Faculty of Medicine of Botucatu, UNESP, Botucatu, SP divided into two groups, pairing by age, being one of the control groups. Anthropometric, blood glucose, triglycerides, total cholesterol and fractions assessment of renal, hepatic, and blood count, serum carotenoids assessment, evaluation of leptin, adiponectin, and insulin and evaluation of malondialdehyde will be analyzing. For analysis of these data will be presented for position and descriptive measures of variability and analyzed by specific tests of comparison. (AU)