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Chewing function on Alzheimer's Disease

Grant number: 13/10200-7
Support Opportunities:Scholarships in Brazil - Doctorate
Effective date (Start): October 01, 2013
Effective date (End): October 22, 2015
Field of knowledge:Health Sciences - Dentistry - Dental Clinics
Principal Investigator:Renata Cunha Matheus Rodrigues Garcia
Grantee:Camila Heitor Campos
Host Institution: Faculdade de Odontologia de Piracicaba (FOP). Universidade Estadual de Campinas (UNICAMP). Piracicaba , SP, Brazil


Alzheimer's disease (AD) is a neurodegenerative disorder in which there is impairment of memory and other cognitive and intellectual functions as well as behavioral disorders. Impacting on oral health, patients with AD present higher incidence of dental problems, fewer occlusal pairs and older dentures, which could affect chewing function. These functions impairment have been pointed as a risk factor for cognitive decline and the development of dementia in the elderly. As mastication is important for maintaining the cognitive function, this research project aims to describe objectively the masticatory function of elderly diagnosed with Alzheimer's disease, and to investigate the association between cognitive and chewing function in those patients. For that, 15 volunteers diagnosed with Alzheimer's disease (experimental group) and 15 with no dementia (control group) will be selected. Chewing function will be assessed by the use of the chewable test material Optocal and the fractionation method by sieves. Cognitive performance will be evaluated by applying the Mini Mental State Examination and the Clinical Dementia Rating Scale. Collected data will undergo exploratory analysis and then appropriate statistical tests will be applied. It is expected to find association between cognitive decline and impaired masticatory function. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
CAMPOS, CAMILA HEITOR; RIBEIRO, GISELLE RODRIGUES; RIANI COSTA, JOSE LUIZ; MATHEUS RODRIGUES GARCIA, RENATA CUNHA. Correlation of cognitive and masticatory function in Alzheimer's disease. CLINICAL ORAL INVESTIGATIONS, v. 21, n. 2, p. 573-578, . (13/10200-7)
CAMPOS, C. H.; RIBEIRO, G. R.; STELLA, F.; RODRIGUES GARCIA, R. C. M.. Mandibular movements and bite force in Alzheimer's disease before and after new denture insertion. Journal of Oral Rehabilitation, v. 44, n. 3, p. 178-186, . (13/10200-7)
CAMPOS, CAMILA H.; RIBEIRO, GISELLE R.; RODRIGUES GARCIA, RENATA C. M.. Mastication and oral health-related quality of life in removable denture wearers with Alzheimer disease. JOURNAL OF PROSTHETIC DENTISTRY, v. 119, n. 5, p. 764-768, . (13/10200-7)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
CAMPOS, Camila Heitor. Oral health perception and chewing function in elderly with Alzheimer's disease. 2015. Doctoral Thesis - Universidade Estadual de Campinas (UNICAMP). Faculdade de Odontologia de Piracicaba Piracicaba, SP.

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