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Values of immunoglobulin G and of acute phase proteins in the blood serum of kids and milk secretions of Saanen goats

Grant number: 13/19553-0
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): October 01, 2013
Effective date (End): September 30, 2014
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
Principal Investigator:Francisco Leydson Formiga Feitosa
Grantee:Murilo Catelani Ferraz
Host Institution: Faculdade de Medicina Veterinária (FMVA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil

Abstract

The supply of colostrum to kids newborns is essential to the transfer of passive immunity because the placenta of bovine ruminants, named epitéliocorial, prevents the passage of antibodies during pregnancy. Apart from immunoglobulins, acute phase proteins are also transferred to the neonate. Acute-phase proteins aid in the early diagnosis of inflammatory diseases. In addition to these colostrais components, the presence or absence of clinical mastitis or asymptomatic can influence the quantity and quality as well as colostral immune elements present, mainly with regard to concentrations of immunoglobulins. Thus, this project aims to evaluate the colostrais secretions of goats with and without mastitis in relation to concentrations of immunoglobulin G, cytokines and acute-phase proteins. For this purpose, samples of colostrum and milk of at least 12 goats will be used. The same determinations will be made in the serum of their kids. Samples of blood and colostrum will be taken soon after birth, and over 48 hours, with the care of asepsis. (AU)

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