Role of neural mobilization technique on inflammatory response and behavior in Wistar rats after induction of neuropathic pain

• Grant number: 13/19837-8
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: December 01, 2013
• End date: December 31, 2015
• Field of knowledge: Biological Sciences - Morphology - Anatomy
• Principal Investigator: Marucia Chacur
• Grantee: Igor Rafael Correia Rocha
• Host Institution: Instituto de Ciências Biomédicas (ICB). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated scholarship(s): 15/00603-2 - Skin biopsy in entrapment neuropathy, BE.EP.IC

Abstract

Neural mobilization technique (MOB) is a noninvasive method which has demonstrated in basic research and in clinical trials to be effective in reducing the sensitivity to pain. The present study aims to examine, through the analysis of cytokines, the effects of MOB on pain sensitivity induced by chronic constriction (CCI) of the sciatic nerve in rats, as well as assess the locomotion of animals by sciatic functional index (SFI).