Development of polymeric biomaterials containing pharmacological activity

• Grant number: 14/00155-7
• Support type: Scholarships in Brazil - Scientific Initiation
• Effective date (Start): March 01, 2014
• Effective date (End): December 31, 2014
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal researcher: Luiz Henrique Catalani
• Grantee: Caroline Guedes Monteiro
• Home Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated research grant: 11/21442-6 - Synthetic and natural polymers applied to tissue engineering, AP.TEM

Abstract

This project aims to study polymers with pharmacological properties (polymer drugs) to produce scaffolds for cell growth. Thus, is intended to study the synthesis and characterization of a poly (anhydride-ester) derived from adipic and salicylic acid, as well as studies of production of blends with poly (L-lactide) (PLLA) and poly(L-lactide-co-glycolide) (PLGA), and the release of salicylic acid under simulated conditions of biodegradation.