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Evaluation of cortisol level, capillary glycemia and blood pressure in response to anxiety in denture wearers

Grant number: 13/17469-1
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): May 01, 2014
Effective date (End): April 30, 2015
Field of knowledge:Health Sciences - Dentistry - Dental Materials
Principal Investigator:Marcelo Coelho Goiato
Grantee:Nádia Biage Cândido
Host Institution: Faculdade de Odontologia (FOA). Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Araçatuba , SP, Brazil


It is known that denture wearers have loss of their quality of life, which may improve their stress levels. The cortisol is one of the main hormones involved in stress situations. To measure the cortisol levels, the salivary sampling is the most indicated. So, the aim of this study is to analyze the patient's stress levels through an anxiety questionnaire (IDATE), the cortisol level present in saliva, capillary glycaemia and blood pressure before and after the dentures installation, evaluating if there is any correlation between these factors. Fifty patients that need to reestablish their oral function with dentures in both arches will be evaluated in this study and included according to the study strategy. Both the questionnaire and the sampling of saliva and blood will be performed before the dentures installation and one month after the last control, preventing any patient's pain and poor denture's adaptation. The sampling of glycaemia, cortisol and the measurement of blood pressure will be performed three times/day. The results will be tabulated with Excel and the statistics analysis will be performed through SPSS program 21.0 edition and submitted to the test of adherence to the normal curve, applying appropriated statistical test to compare the obtained results.

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