Cervical cancer in Campinas and region in the period from 2000 to 2011: review of the evolution of age, histological type and stage at diagnosis

• Grant number: 14/02595-4
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: July 01, 2014
• End date: June 30, 2015
• Field of knowledge: Health Sciences - Medicine - Maternal and Child Health
• Principal Investigator: Júlio César Teixeira
• Grantee: Mariana Sollia Soares
• Host Institution: Centro de Atenção Integral à Saúde da Mulher (CAISM). Hospital da Mulher Professor Doutor José Aristodemo Pinotti. Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

Cervical cancer is the third most often malignant neoplasm among women in Brazil, leading to about eight thousand deaths each year in our country. It is a preventable disease and it has a known etiology (Human papilomavirus, HPV) making it possible and necessary the screening of precursor lesions through organized programs that use cervical cytology or other tests, aiming a diagnosis of controllable lesions. The programs that already exist vary in age of beginning and termination, and the periodicity of cytology. Still, the lack of organized application of these programs makes this cancer continues happening, even though with the passing of time and depending on the organization at each site, there is a tendency of diagnosis in early stages. Other expected changes may be a higher proportion of adenocarcinomas detection and higher number of diagnosis in young women, two situations related to worse prognosis. To define the evolutionary overview of how the region of Campinas fits this change, the cases of cervical cancer and NIC3 diagnosed in the period 2000-2011 will be analyzed through a retrospective descriptive study that will analyze information obtained from hospital medical records of Women's Hospital and the Department of Pathology at Unicamp records. Therefore, the evolution of the global annual incidence by age, stage and histological type, will be analyzed by the Fisher test or chi-square, Mann-Whitney test, p <0.05 for statistical significance and fitted curves of Kaplan Meyer-for accumulated and analyzed by using the log-rank test impact. With the obtained results, there will be an idea of the effectiveness of control measures adopted in the area of cancer, and may help health managers in the assessment of the applied program and future directions. (AU)