| Grant number: | 13/15154-3 |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| Start date: | July 01, 2014 |
| End date: | August 15, 2017 |
| Field of knowledge: | Health Sciences - Medicine - Pathological Anatomy and Clinical Pathology |
| Agreement: | Coordination of Improvement of Higher Education Personnel (CAPES) |
| Principal Investigator: | Paulo Hilário Nascimento Saldiva |
| Grantee: | Carolina Letícia Zilli Vieira |
| Host Institution: | Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil |
| Associated scholarship(s): | 15/03893-1 - Analysis of the association between galactic cosmic ionization, air pollution and mortality in U.S. cities since 1990, BE.EP.PD |
Abstract For centuries, infectious diseases represent, along with the wars and famine, one of the hallmarks of progress and human survival. They are responsible for 26% of deaths on the Planet, and the second cause of death behind cardiovascular disease. Although there are so many methods of control of some remerge diseases in public health systems, epidemics of new and old infectious diseases re/emerge periodically causing great impact on overall disease profile. Studies of re/emerging infectious reveal developmental properties of the pathogenic microorganisms and a dynamic relationship between these, and the host environment. Understanding the nature of re/emerging infections pandemics and their consequence is essential for control and prevention of these diseases, especially in a period marked by changes in the environment and climate. Different intensities of solar radiation and galactic cosmic radiation (GCR) are frequently observed during solar cycles. These radiations seem to lead to climate change, as well as changes in the chemical and biological aspects of life on the planet. The ionization of the lower atmosphere generated by the RGC and solar radiation may have effects on the evolutionary mechanisms of all living beings, including animals and microorganisms hosts, forcing them to adapt to changes in the environment. Consequently modifying the pathogenic action of these microorganisms, and resulting in the permanency of re/emergence of infections in human. Objectives: Observing changes in solar and galactic cosmic radiation during solar cycles of 11 years and their possible associations with the re / emergence of infectious diseases, this study aims to evaluate the correlation between the periodic changes in solar radiation, galactic cosmic radiation and re-incidence of infectious diseases re / emerging since 1930 in the city of São Paulo. Methods: The association between the variables described above will be made initially through the descriptive analysis of the data collected and, subsequently, by building multiple regression models using SPSS 17 statistical program and R. The analysis is performed by associating annual records of solar activity and GCR , during the 11-year cycles, with the incidence of mortality from infection re / emerging most commonly recorded in the database of SEADE Foundation and the Department of Pathology of the USP that these records exist since 1930. The data of solar activity and RGC will be obtained at the National Oceanic and Atmospheric Administration (NOAA). (AU) | |
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