Evaluation of the influence on cytokine production profile of immune response in calves in the first 30 days of life

• Grant number: 14/02418-5
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: August 01, 2014
• End date: February 28, 2017
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
• Agreement: Coordination of Improvement of Higher Education Personnel (CAPES)
• Principal Investigator: Fernando Jose Benesi
• Grantee: Carolina de Lara Shecaira
• Host Institution: Faculdade de Medicina Veterinária e Zootecnia (FMVZ). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The first 30 days of life of calves, called the neonatal period is a period of great immunological development. However, several peculiarities in the development of the fetal immune system and the calf in his early postnatal days, makes a moment of immunological vulnerability. Understanding this development is extremely important because this will determine the ability of the calf to become an adult and healthy animal. Therefore, it is proposed in this study to evaluate the pattern of immune response of the neonate in the first 30 days of life, through reviews: phagocytic activity and oxidative metabolism of circulating neutrophils, the relationship between the quantities of CD4 + and CD8 + and circulating cytokine profile of Th1 and Th2. Determining the relation between quality of transfer of passive immunity and the subsequent immune response of the neonate. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

SHECAIRA, C. L.; SEINO, C. H.; BOMBARDELLI, J. A.; REIS, G. A.; FUSADA, E. J.; AZEDO, M. R.; BENESI, F. J.. Using thermography as a diagnostic tool for omphalitis on newborn calves. Journal of Thermal Biology, v. 71, p. 209-211, JAN 2018. (14/02418-5, 13/25323-7)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

SHECAIRA, Carolina de Lara. Evaluation of the influence of cytokine production on the immune response profile of calves in the first 30 days of life. 2017. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Medicina Veterinária e Zootecnia (FMVZ/SBD) São Paulo.