Laser and X-ray induced photoacoustic imaging

• Grant number: 15/05684-0
• Support Opportunities: Scholarships in Brazil - Doctorate
• Effective date (Start): June 01, 2015
• Effective date (End): August 26, 2018
• Field of knowledge: Engineering - Biomedical Engineering - Bioengineering
• Acordo de Cooperação: Coordination of Improvement of Higher Education Personnel (CAPES)
• Principal Investigator: Theo Zeferino Pavan
• Grantee: Diego Ronaldo Thomaz Sampaio
• Host Institution: Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated research grant: 13/18854-6 - Photoacoustic and ultrasound imaging applied to tissue characterization, AP.JP
• Associated scholarship(s): 16/22720-3 - Photoacoustic waves and ionizing radiation: laser and X-ray photoacoustic imaging, BE.EP.DR

Abstract

Photoacoustic imaging (PA) is a new image modality, for evaluating optical and mechanical characteristics of tissue. The physical principle consists in the use of electromagnetic radiation to generate acoustic pressure waves, due to photons absorption and subsequently thermal expansion, which are received by ultrasound equipment. Many researches have been developed PA applications using visible light optical spectra. However, only a few studies have reported the use of X-ray photons to produce photoacoustic images and biomedical applications. The X-ray scatter in tissue is much lower than optical photons, which could potentially increase de depth of penetration of PA, increasing, therefore, the range of possible applications. In this project, we aim to investigate PA imaging using X-ray photons to generate PA signals to measure the dose of radiation deposited during a radiation therapy procedure. Moreover, we propose to study PA physical mechanism to develop an acquisition system for PA and to implement computational routines to reconstruct PA image from X-ray beams. Therefore, we intend to provide a dose monitoring system during radiotherapy treatment based on ultrasound and PA. (AU)

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

. Photoacoustic-based thermal image formation and optimization using an evolutionary genetic algorithm. Res. Biomed. Eng., n. ahead, p. -, 2018. (15/05684-0, 13/18854-6, 14/26598-2)

SAMPAIO, DIEGO R. T.; YALY, CAROLINA C.; PAVONI, JULIANA F.; CARNEIRO, ANTONIO A. O.; PAVAN, THEO Z.. Radiotherapy Linear Accelerator-Based X-Ray Acoustic Imaging Using Linear Array Transducer and Its Relationship with Dose: Multidomain Simulation and In Vitro Experiments. Brazilian Journal of Physics, v. 51, n. 4, p. 1069-1078, AUG 2021. (15/05684-0, 13/18854-6)

ULIANA, JOAO H.; SAMPAIO, DIEGO R. T.; FERNANDES, GUILHERME S. P.; BRASSESCO, MARIA S.; NOGUEIRA-BARBOSA, MARCELLO H.; CARNEIRO, ANTONIO A. O.; PAVAN, THEO Z.. Multiangle Long-Axis Lateral Illumination Photoacoustic Imaging Using Linear Array Transducer. SENSORS, v. 20, n. 14, JUL 2020. (17/14482-8, 16/22374-8, 13/18854-6, 15/05684-0)

JOÃO HENRIQUE ULIANA; DIEGO RONALDO THOMAZ SAMPAIO; ANTONIO ADILTON OLIVEIRA CARNEIRO; THEO ZEFERINO PAVAN. Photoacoustic-based thermal image formation and optimization using an evolutionary genetic algorithm. Res. Biomed. Eng., v. 34, n. 2, p. 147-156, 2018-05-28. (14/26598-2, 13/18854-6, 15/05684-0)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

SAMPAIO, Diego Ronaldo Thomaz. Laser and X-Ray induced photoacoustic imaging. 2020. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (PCARP/BC) Ribeirão Preto.