Structural and molecular analysis of the hypotalamus median eminence of mice born from high fat diet fed mothers

• Grant number: 15/02913-9
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Effective date (Start): May 01, 2015
• Effective date (End): April 30, 2018
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Principal Investigator: Licio Augusto Velloso
• Grantee: Roberta Haddad Tóvolli
• Host Institution: Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 13/07607-8 - OCRC - Obesity and Comorbidities Research Center, AP.CEPID
• Associated scholarship(s): 16/01868-2 - Translatome analysis of mouse POMC neurons and epigenetic analysis of the median eminence BBB in diet-induced obese offspring, BE.EP.PD

Abstract

A postdoctoral position is available at the Obesity and Comorbidities Research Center, University of Campinas - Brazil. The scientific aim of the project is to investigate the patterning, structure and function of the median eminence of embryos and mice born from high fat diet fed mothers. The fellowship is funded by São Paulo Research Foundation. We are seeking applicants who are exceptionally motivated, innovative, and can work independently within a collaborative team setting. The desired candidate must have excellent background in the field of biological sciences. Wide experience in hypothalamic development, anatomy and histology, immunohistochemistry techniques, molecular biology and cloning are expected. The candidate must control embryonic genetic manipulation techniques such as in utero electroporation and viral transfection. The position requires excellent written and oral communication skills.Obesity and Comorbidities Research Center is a non- profit organization devoted to the research of obesity and related disorders. OCRC is affiliated to the University of Campinas. Our research facility is located in Campinas SP - Brazil.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

HADDAD-TOVOLLI, ROBERTA; DRAGANO, NATHALIA R. V.; RAMALHO, ALBINA F. S.; VELLOSO, LICIO A.. Development and Function of the Blood-Brain Barrier in the Context of Metabolic Control. FRONTIERS IN NEUROSCIENCE, v. 11, APR 21 2017. (15/50278-0, 15/02913-9, 14/26942-5, 16/01868-2, 13/07607-8)

HADDAD TOVOLLI, ROBERT; MORARI, JOSEANE; BARBIZAN, ROBERTA; BOBBO, VANESSA C.; S. CARRARO, RODRIGO; SOLON, CARINA; DRAGANO, NATHALIA R.; TORSONI, MARCIO A.; P. ARAUJO, ELIANA; VELLOSO, LICIO A.. Maternal obesity damages the median eminence blood-brain barrier structure and function in the progeny: the beneficial impact of cross-fostering by lean mothers. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, v. 324, n. 2, p. 13-pg., 2023-02-01. (15/02913-9, 13/07607-8)