Seven yeast populations (4 sexual and 3 clonal) will be propagated against a gradient of increasing ethanol concentration in the growth medium. The internship student will help with the routine of cultivation, which will include periodic fitness and competition assays. The student will be introduced to genomic techniques used for comparative genetic analysis of sexual and clonal yeast populations. The mutations found will be further inspected by molecular and physiologic methods. In this context, the student will be assigned a particular mutant allele as his main object of study. The goal is to introduce the student to several aspects of modern genomics and molecular genetics, aiming at shaping the education of future researchers in those fields.
News published in Agência FAPESP Newsletter about the scholarship: