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Evolution of meiosis and sex in Amoebozoa

Grant number: 15/06306-0
Support type:Scholarships in Brazil - Doctorate
Effective date (Start): August 01, 2015
Effective date (End): July 31, 2019
Field of knowledge:Biological Sciences - Genetics - Molecular Genetics and Genetics of Microorganisms
Principal researcher:Daniel José Galafasse Lahr
Grantee:Paulo Gonzalez Hofstatter
Home Institution: Instituto de Biociências (IB). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Associated scholarship(s):17/04391-5 - Evolution of meiosis in eukaryotes, BE.EP.DR


Amoeboid protists have always raised intriguing questions about sex in eukaryotes. Classical studies failed to detect meiotic process or sex in several groups. The advent of modern techniques allows for the study of eukaryotic sex at the level of genes known to be involved in the process. Recent phylogenetic studies have demonstrated probable evolutionary relationships among diverse amoebozoan groups, but the presumed asexual lineages do not form a clade in any modern phylogenies. Sex might have been lost several times among members of Amoebozoa, but which evolutionary pressures would drive sexual lineages to an asexual way of life? Would sex have been lost at all? (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
HOFSTATTER, PAULO G.; TICE, ALEXANDER K.; KANG, SEUNGHO; BROWN, MATTHEW W.; LAHR, DANIEL J. G.. Evolution of bacterial recombinase A (recA) in eukaryotes explained by addition of genomic data of key microbial lineages. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, v. 283, n. 1840, . (15/06306-0)
HOFSTATTER, PAULO G.; BROWN, MATTHEWW.; LAHR, DANIEL J. G.. Comparative Genomics Supports Sex and Meiosis in Diverse Amoebozoa. GENOME BIOLOGY AND EVOLUTION, v. 10, n. 11, p. 3118-3128, . (15/06306-0, 13/04585-3)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
HOFSTATTER, Paulo Gonzalez. Evolution of meiosis and sex in Amoebozoa. 2019. Doctoral Thesis - Universidade de São Paulo (USP). Instituto de Biociências (IBIOC/SB) São Paulo.

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