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Autonomic function of household passive smokers adults

Grant number: 15/10350-4
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): August 01, 2015
Effective date (End): July 31, 2016
Field of knowledge:Health Sciences - Physiotherapy and Occupational Therapy
Principal Investigator:Ercy Mara Cipulo Ramos
Grantee:Vanessa de Melo Dantas
Home Institution: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil

Abstract

Background: Autonomic Nervous System (ANS) is altered in active smokers and the influence of passive exposure to cigarette smoke in healthy individuals, who live with smokers, is still unclear in the literature. So it becomes necessary to know the extent of the damage in (SNA) in individuals exposed to passive smoking. Objective: To evaluate the autonomic function of adults exposed to household passive smoking. Methods: The study was approved by the Institutional Committee, CAAE Protocol: 07152212.0.0000.5402. We will asses 76 individuals, divided into two groups: passive smokers group (PSG), and the control group (CG). The autonomic function will be assessed by heart rate variability (HRV) indices at rest, through the heart rate monitor Polar S810i. Linear methods, time-domain (TD) and frequency domain ( FD) will be analyzed 20 minutes. In TD, the RMSSD and SDNN (ms) indexes will be calculated. For analysis in the FD, the spectral components of low frequency (LF) will be monitored in ms2 and normalized units (nu) and high frequency (HF ms2 and nu) and the ratio of these components (LF / HF). Statistical Analysis: Data will be analyzed by GraphpadPrism® statistical program. The normal distribution of the data will be evaluated by the Shapiro-Wilk test. For intergroup analysis Student's t test unpaired will be used if there is no data normality, the Mann-Whitney test is applied. For the correlation the Pearson test for normal data will be used and Spearman for data non normal. The level of significance employed will be p <0.05.