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Development of modified TPLO plate and comparative biomechanical test with other two methods of bone stabilization (locking plate and locking plate associated with intramedullary pin) in experimental proximal gap in synthetic tibias

Grant number: 15/14602-8
Support Opportunities:Scholarships in Brazil - Master
Effective date (Start): October 01, 2015
Effective date (End): February 28, 2017
Field of knowledge:Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
Principal Investigator:Luis Gustavo Gosuen Gonçalves Dias
Grantee:Guilherme Sembenelli
Host Institution: Faculdade de Ciências Agrárias e Veterinárias (FCAV). Universidade Estadual Paulista (UNESP). Campus de Jaboticabal. Jaboticabal , SP, Brazil


The aim of this study is to develop modified locking TPLO plate and evaluate the effectiveness of bone stabilization provided by the implant developed compared with other two methods of conventional bone fixation (locking plate and locking plate associated with intramedullary pin). Through of biomechanical studies will be verified which construction is more resistant to rotational, bending and axial forces in proximal gap in canine synthetic tibia. The modified TPLO plate that will be developed in this study, after studies, it will can be used in a minimally invasive surgery allowing the insertion of a greater number of screws in the proximal fragment, through a small surgical approach. Sixty synthetic tibiae are used which will be divided into three groups. Group 1 (modified TPLO plate) will be subdivided into four groups of five tibias, G1FMD (mediolateral bending), G1FCD (caudocranial bending), G1R (rotation) and G1A (axial loading). Similarly the Group 2 (locking plate) is subdivided into four groups of five tibia, G2FMD (mediolateral bending), G2FCD (caudocranial bending), G2R (rotation) and G2A (axial loading) and Group 3 (locking plate associated with intramedullary pin) subdivided into four groups of five tibia, G3FMD (mediolateral bending), G3FCD (caudocranial bending), G3R (rotation) and G3A (axial loading). Testing should be performed until assembly failure (implants and/or tibia). The data will be submitted to normality test and evaluated by analysis of variance (ANOVA) at the 5% significance. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
G. SEMBENELLI; G.V. SOUZA; M.C.N. WITTMAACK; A.C. SHIMANO; T.A.S.S. ROCHA; P.C. MORAES; B.W. MINTO; L.G.G.G. DIAS. [Comparação biomecânica entre placa de TPLO modificada, placa bloqueada e construção placa-pino intramedular aplicadas medialmente em modelo de fratura proximal em tíbias sintéticas caninas]. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, v. 74, n. 5, p. 948-953, . (15/14602-8)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
SEMBENELLI, Guilherme. Biomechanical analysis of modified plate of tplo in experimental model of proximal gap in synthetic tíbias canines. 2017. Master's Dissertation - Universidade Estadual Paulista (Unesp).

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