Advanced search
Start date

Thermoanalytical studies, synthesis and characterization of the solid co-crystals of ciprofloxacin with some co-formers

Grant number: 15/19863-4
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): February 01, 2016
Effective date (End): July 31, 2018
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
Principal researcher:Flávio Junior Caires
Grantee:Carolina Torquetti
Home Institution: Faculdade de Ciências (FC). Universidade Estadual Paulista (UNESP). Campus de Bauru. Bauru , SP, Brazil


This project aims at the synthesis and characterization of solid co-crystals obtained from ciprofloxacin with the co-formers caffeic acid, ferulic acid, p-coumaric acid and chlorogenic acid.The crystals will be obtained through mechanochemical methods (solvent free and/or solvent-assisted grinding), with the aid of a ball mill. The characterization of the co-crystals will be carried out through the following experiments: differential scanning calorimetry (DSC) with microscope system, absorption spectroscopy in the infrared region (FTIR) and X-ray diffraction techniques (powder method and single crystal). It is expected this way to obtain co-crystals capable of promote an improvement in the physico-chemical properties of the antibiotic drug used for this study.

News published in Agência FAPESP Newsletter about the scholarship:
Articles published in other media outlets (0 total):
More itemsLess items

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
TORQUETTI, CAROLINA; FERREIRA, PATRICIA OSORIO; DE ALMEIDA, AMANDA COSMO; FERNANDES, RICHARD PEROSA; CAIRES, FLAVIO JUNIOR. Thermal study and characterization of new cocrystals of ciprofloxacin with picolinic acid. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, v. 147, n. 2, p. 1299-1306, . (18/24378-6, 17/14936-9, 13/09022-7, 15/19863-4)

Please report errors in scientific publications list by writing to: