Prostate cancer (PCa) is a commonly diagnosed cancer among men around the world. The detection of PCain early stages can help clinicians to administer an effective and preventive treatment. For this purpose, theaim of this project is the development of a sensitive, portable, cheap and multiplexable biosensor. This is alabel-free electrochemical multiplexing assay which has specific electrode-immobilised biomarkers (PAP,fPSA and tPSA) for the premature diagnostic of prostate cancer. Label-free detection has many advantagesover the labelled techniques as the quicker protocols, reducing the background signal and higher levels ofsensitivity. Our biosensor is based in impedance/capacitance measurements of the electrode-solutioninterface. If there is interaction between the target analyte in the sample and the electrode-immobilisedbiomarker, the measure will change detectably.
News published in Agência FAPESP Newsletter about the scholarship: