Antifungal activity and cytotoxicity of biomaterials coated with chitosan nanoparticles containing salivary proteins molecules, histatin 1, histatin 5 or DR9RR14 encapsulated, in co-culture

• Grant number: 15/06016-1
• Support Opportunities: Scholarships in Brazil - Doctorate
• Effective date (Start): January 01, 2016
• Effective date (End): July 31, 2018
• Field of knowledge: Health Sciences - Dentistry - Dental Materials
• Principal Investigator: Janaina Habib Jorge
• Grantee: Cláudia Viviane Guimarães Pellissari
• Host Institution: Faculdade de Odontologia (FOAr). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil
• Associated scholarship(s): 18/13904-9 - Evaluation of novel salivary peptides for treatment of oral candidiasis, BE.EP.DR

Abstract

The propose of this study will be evaluating the antifungal activity and cytotoxicity of biomaterials coated with chitosan nanoparticles containing salivary proteins molecules, histatin 1, histatin 5 or DR9RR14 encapsulated, in co-culture.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

GUIMARAES PELLISSARI, CLAUDIA VIVIANE; JORGE, JANAINA HABIB; MARIN, LINA MARIA; SABINO-SILVA, ROBINSON; SIQUEIRA, WALTER LUIZ. Statherin-derived peptides as antifungal strategy against Candida albicans. ARCHIVES OF ORAL BIOLOGY, v. 125, MAY 2021. (16/03847-2, 15/06016-1, 18/13904-9)