Chromatographic and electroanalytical methods applied in determination of p-toluenediamine and p-aminophenol in oxidative medium used in permanent hair dye.

• Grant number: 15/12998-1
• Support Opportunities: Scholarships in Brazil - Doctorate
• Effective date (Start): April 01, 2016
• Effective date (End): March 31, 2020
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Maria Valnice Boldrin
• Grantee: João Carlos de Souza
• Host Institution: Instituto de Química (IQ). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil
• Associated scholarship(s): 18/12449-6 - Study of the electrochemical behavior of keratin and its interaction with p-toluenediamine and p-aminophenol and their oxidation products mimicking reactions of permanent hair dye, BE.EP.DR

Abstract

The permanent dyeing of hair is a process adopted by millions of people worldwide, and involves complex oxidative reactions between precursor agents and couplers in medium alkaline oxidant inside the hair. The project proposes to improve understanding of these reactions, investigating the reaction between p-toluenediamine and p-aminophenol as models of compounds of permanent dyes for chromatographic techniques with mass detector and spectrophotometry in the UV-VIS region. It is also our proposal to seek new analytical methodologies for the determination of these compounds and its derivatives in hairdressing salons wastewater and water abstraction in water treatment stations using electrochemical sensors and high-performance liquid chromatography coupled with electrochemical detector. For this it is intended to exploit the policysteine and keratine as an example of modifiers in gold electrodes and printed electrodes grapheme, respectively, since both are basic constituents of the hair.

Scientific publications

(10)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

BESSEGATO, GUILHERME GARCIA; DE SOUZA, JOAO CARLOS; CARDOSO, JULIANO CARVALHO; BOLDRIN ZANONI, MARIA VALNICE. Assessment of several advanced oxidation processes applied in the treatment of environmental concern constituents from a real hair dye wastewater. JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, v. 6, n. 2, p. 2794-2802, APR 2018. (14/03679-7, 15/18109-4, 15/12998-1)

DE SOUZA, JOAO CARLOS; DA SILVA, BIANCA FERREIRA; MORALES, DANIEL ALEXANDRE; UMBUZEIRO, GISELA DE ARAGAO; BOLDRIN ZANONI, MARIA VALNICE. Assessment of p-aminophenol oxidation by simulating the process of hair dyeing and occurrence in hair salon wastewater and drinking water from treatment plant. JOURNAL OF HAZARDOUS MATERIALS, v. 387, APR 5 2020. (14/50945-4, 15/18109-4, 15/12998-1, 08/10449-7)

DE SOUZA, JOAO CARLOS; DA SILVA, BIANCA FERREIRA; MORALES, DANIEL ALEXANDRE; UMBUZEIRO, GISELA DE ARAGAO; BOLDRIN ZANONI, MARIA VALNICE. Assessment of the autoxidation mechanism of p-toluenediamine by air and hydrogen peroxide and determination of mutagenic environmental contaminant in beauty salon effluent. Science of The Total Environment, v. 685, p. 911-922, OCT 1 2019. (15/12998-1, 14/03679-7)

DE SOUZA, JOAO CARLOS; BOLDRIN ZANONI, MARIA VALNICE; OLIVEIRA-BRETT, ANA MARIA. Reprint of "Genotoxic permanent hair dye precursors p-aminophenol and p-toluenediamine electrochemical oxidation mechanisms and evaluation in biological fluids". JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 872, p. 7-pg., 2020-09-01. (18/12449-6, 15/12998-1, 14/50945-4)

HUDARI, FELIPE FANTINATO; SOUZA, JOAO CARLOS; BOLDRIN ZANONI, MARIA VALNICE. Adsorptive stripping voltammetry for simultaneous determination of hydrochlorothiazide and triamterene in hemodialysis samples using a multi-walled carbon nanotube-modified glassy carbon electrode. Talanta, v. 179, p. 652-657, MAR 1 2018. (15/18109-4, 15/12998-1)

DE SOUZA, JOAO CARLOS; DA SILVA, JOSE LUIZ; FABRAO, RODRIGO MONTEIRO; STRADIOTTO, NELSON RAMOS; BOLDRIN ZANONI, MARIA VALNICE. Electroactive sugars, organic acids and sugar alcohol analysis in wine using anion-exchange chromatography with electrochemical detection. Microchemical Journal, v. 147, p. 972-978, JUN 2019. (14/03679-7, 15/12998-1)

DE SOUZA, JOAO CARLOS; BOLDRIN ZANONI, MARIA VALNICE; OLIVEIRA-BRETT, ANA MARIA. Genotoxic permanent hair dye precursors p-aminophenol and p-toluenediamine electrochemical oxidation mechanisms and evaluation in biological fluids. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, v. 857, JAN 15 2020. (14/50945-4, 18/12449-6, 15/12998-1)

CORREA, GLAUCIA TINOCO; DE SOUZA, JOAO CARLOS; SILVA, JOAO PEDRO; PIVIDORI, MARIA ISABEL; BOLDRIN ZANONI, MARIA VALNICE. Determination of temporary dye Basic Red 51 in commercial hair dye, river water and wastewater from hairdressing salon using graphite-epoxy composite electrode modified with magnetic nanoparticles. Microchemical Journal, v. 159, DEC 2020. (13/21542-6, 15/12998-1, 14/50945-4)

DE SOUZA, JOAO CARLOS; DA SILVA, BIANCA FERREIRA; MORALES, DANIEL ALEXANDRE; UMBUZEIRO, GISELA DE ARAGAO; BOLDRIN ZANONI, MARIA VALNICE. Assessment of the compounds formed by oxidative reaction between p-toluenediamine and p-aminophenol in hair dyeing processes: Detection, mutagenic and toxicological properties. Science of The Total Environment, v. 795, NOV 15 2021. (14/50945-4, 15/12998-1)

DE SOUZA, JOAO CARLOS; IRIKURA, KALLYNI; MANTILLA, HERNAN DARIO ROJAS; ZANONI, MARIA VALNICE BOLDRIN; SALAZAR, RICARDO. Using 3D printed magnetic platform as support for screen printed electrode applied for p-toluenediamine detection in biological fluid and water samples. Analytica Chimica Acta, v. 1240, p. 13-pg., 2022-12-30. (19/13113-4, 15/12998-1, 14/50945-4)