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Chemical study of fungus Stachybotrys levipora: use of precursors to obtain new metabolites

Grant number: 16/08616-9
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): June 01, 2016
Effective date (End): May 31, 2017
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Organic Chemistry
Principal Investigator:Maria Fátima das Graças Fernandes da Silva
Grantee:Adriele Ribeiro dos Santos
Home Institution: Centro de Ciências Exatas e de Tecnologia (CCET). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil
Associated research grant:12/25299-6 - Integrated studies for leaf cutting control, AP.TEM


Necessity to employ alternative strategies for the reduction and rational use of pesticides, has been encouraging Brazilian to use the biodiversity as a natural source of bioactive compounds in combating pests, insects, fungi and weeds. Recent studies, pointed to use of fungi as natural source saprobes quite effective. They can contributes to the disease and pest control through the activation of defense mechanisms in susceptible plants, and/or by the direct activity antagonism. Additional, having great potential as a source of new substances that may be explored in pharmaceutics. In this context, the chemical study of Stachybotrys levispora it is necessary, because in some preliminary studies conducted by the group of natural products UFSCar, showed great potential for the production of metabolites interesting from the point of view of biological activity.