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Risk management of sexual transmission of HIV among people living with HIV / AIDS

Grant number: 15/23008-2
Support type:Scholarships abroad - Research
Effective date (Start): November 20, 2016
Effective date (End): July 19, 2017
Field of knowledge:Health Sciences - Nursing - Infectious Diseases Nursing
Principal researcher:Renata Karina Reis
Grantee:Renata Karina Reis
Host: Bruno Spire
Home Institution: Escola de Enfermagem de Ribeirão Preto (EERP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
Research place: Aix-Marseille Université (AMU), France  


Despite remarkable advancements in the last 30 years, Human Immunodeficiency Virus (HIV) remains a major threat to public health. While the number of new HIV infections has decreased in different regions of the world and even in Latin America in 2005-2013, in Brazil the number of new infections increased 11% in the same period. Therefore, there is a need to improve coping with the AIDS epidemic in Brazil. Challenges still persist in regard to how sexuality is approached in Brazil and, despite the growing role of serodiscordance in the global epidemic of HIV/AIDS, strategies specifically focused on couples with mixed HIV status are either non-existent or inadequate. Hence, the implementation and efficacy of combined preventive strategies for the reduction of the sexual transmission of HIV has been the focus of many studies. The management of the risk of the sexual transmission of HIV on the part of people living with HIV/AIDS and their partners should be included in counseling provided by the health staff to help these individuals make informed decisions about the efficacy of the single use of a given preventive method or the combination of methods in avoiding the sexual transmission of HIV. Thus, this study's general objective is to analyze predictors for the management of the sexual transmission of HIV and other sexually transmissible infections and its association with sociodemographic, behavioral, clinical and psychosocial aspects. This prospective, analytical study will be conducted in a city in the interior of São Paulo, Brazil in the specialized services for HIV/AIDS (SAE). Data will be collected through individually applied semi-structured interviews. The study participants will include individuals living with HIV/AIDS, 18 years old or older, in clinical-ambulatory follow-up provided by the services selected, with medical visits scheduled during the study period, and with a sexual partner who is HIV negative. Data will be doubled entered and organized in spreadsheets in Microsoft Excel and then statistically analyzed using the Statistical Package for the Social Sciences (SPSS) version 17.0. Descriptive statistics will be used to characterize the participants in regard to the variables collected. The Chi-square test will be used to verify association between the study's variables and the variables related to risk management. Afterwards, the predictors will be analyzed using univariate and multivariate logistic regression models, calculating raw and adjusted Odds Ratio (OR) with their respective confidence intervals at 95%. P-values below 0.05 will be considered significant. The study will be submitted to the Institutional Review Board at the University of São Paulo at Ribeirão Preto, College of Nursing. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
REIS, RENATA KARINA; MILANES SOUSA, LAELSON ROCHELLE; MELO, ELIZABETE SANTOS; FERNANDES, NILO MARTINEZ; SORENSEN, WILLIAM; GIR, ELUCIR. Predictors of HIV Status Disclosure to Sexual Partners Among People Living with HIV in Brazil. AIDS AND BEHAVIOR, v. 25, n. 11, p. 3538-3546, NOV 2021. Web of Science Citations: 0.
MILANES SOUSA, LAELSON ROCHELLE; ELIAS, HENRIQUE CIABOTTI; FERNANDES, NILO MARTINEZ; GIR, ELUCIR; REIS, RENATA KARINA. Knowledge of PEP and PrEP among people living with HIV/aids in Brazil. BMC PUBLIC HEALTH, v. 21, n. 1 JAN 7 2021. Web of Science Citations: 0.
RENATA KARINA REIS; ELIZABETE SANTOS MELO; NILO MARTINEZ FERNANDES; MARCELA ANTONINI; LIS APARECIDA DE SOUZA NEVES; ELUCIR GIR. Uso inconsistente do preservativo entre parcerias sexuais sorodiferentes ao vírus da imunodeficiência humana. Revista Latino-Americana de Enfermagem, v. 27, p. -, 2019. Web of Science Citations: 0.

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