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Lactic acid production from lignocellulosic hydrolysate using cell recycling fermentation of Bacillus coagulans

Grant number: 16/14830-3
Support Opportunities:Scholarships abroad - Research Internship - Doctorate (Direct)
Effective date (Start): February 01, 2017
Effective date (End): November 30, 2017
Field of knowledge:Engineering - Chemical Engineering - Chemical Process Industries
Principal Investigator:Rubens Maciel Filho
Grantee:Regiane Alves de Oliveira
Supervisor: Joachim Venus
Host Institution: Faculdade de Engenharia Química (FEQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Research place: Leibniz Institute for Agricultural Engineering and Bioeconomy (ATB), Germany  
Associated to the scholarship:13/26290-5 - Optimization of lactic acid production from sugar cane, BP.DD


Lactic acid is a compound that may be produced trough sugars fermentation and it is used in food, pharmaceutical, medical and chemical industries. It has emerged as a potential chemical compound to the synthesis of renewable and biodegradable plastics, such as polylactic acid, including its uses in the medical field, as well as possible precursor (building block) of other high cost molecules for the chemical industry. However, lactic acid use on industrial scale is still limited due to the relatively high cost of production, when compared to petrochemical products. In order to produce economically feasible and competitive lactic acid by fermentation it is necessary to keep low costs, which is linked to the process performance as well as raw material prices. Therefore, carbon sources such as lignocellulosic materials can be quite promising, since these materials prevent competition with food supply and are directly related to the increased interest on reuse of waste sources, which is an important issue regarding to environment and legislation concern. Moreover, lignocellulosic materials are relatively cheap, abundant and renewable. It has motivated the industry to consider these residues as a carbon source for production of various materials (second generation products). In this sense, the objective of this research work is to optimize the 2G-lactic acid production by fermentation of hydrolyzed lignocellulosic material (Sugar Beet Pulp as a model material), using the microorganism Bacillus coagulans. This investigation will provide the background for the application of other feedstock as sugarcane bagasse. (AU)

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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DE OLIVEIRA, REGIANE ALVES; SCHNEIDER, ROLAND; LUNELLI, BETANIA HOSS; VAZ ROSSELL, CARLOS EDUARDO; MACIEL FILHO, RUBENS; VENUS, JOACHIM. A Simple Biorefinery Concept to Produce 2G-Lactic Acid from Sugar Beet Pulp (SBP): A High-Value Target Approach to Valorize a Waste Stream. Molecules, v. 25, n. 9, . (13/26290-5, 16/14830-3)

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