Redox-inactive metal ions and the modulation of triplet-excited flavin reactivity towards amino acids and peptides

• Grant number: 16/16619-8
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: November 01, 2016
• End date: December 31, 2016
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Physical-Chemistry
• Principal Investigator: Daniel Rodrigues Cardoso
• Grantee: Jéssica Freire Feitor
• Host Institution: Instituto de Química de São Carlos (IQSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil

Abstract

Milk and dairy products are sensitive to light exposure which leads to off-flavor development and reduced nutritional quality. Light-induced oxidation of milk and dairy products impact in the sensory acceptance of the product and reduce shelf-life. Riboflavin plays the major role in the photooxidation of important nutrients in milk and dairy products acting as type I photosensitizer. The reactivity of triplet excited riboflavin towards dairy products constituents are well reported, however the impact of redox inactive metal ions like Ca (II) and Zn (II) in the electron-transfer reaction has not been investigated in so far. Herein, we aim to understand the impact of redox-inactive naturally present metal ions in the reactivity of amino acids and peptides towards triplet excited riboflavin.