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Optimization of epileptic seizure detectors through machine learning techniques.

Grant number: 16/19080-2
Support type:Scholarships in Brazil - Master
Effective date (Start): January 01, 2017
Effective date (End): April 30, 2017
Field of knowledge:Engineering - Electrical Engineering - Industrial Electronics, Electronic Systems and Controls
Principal Investigator:Fernando José von Zuben
Grantee:Fernando dos Santos Beserra
Home Institution: Faculdade de Engenharia Elétrica e de Computação (FEEC). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Associated research grant:13/07559-3 - BRAINN - The Brazilian Institute of Neuroscience and Neurotechnology, AP.CEPID


Among the various research niches in epilepsy, scientists and computer engineers have been contributing with methods for the detection and prediction of seizures, as well as with the location of epileptic foci. A common challenge is represented by the inherent variability of the disease and the scarcity of data containing seizure onset time and length, usually making most optimized solutions found for a particular patient of poor performance when applied to other patients, highlighting the need for developing software solutions with greater inter-individual generalization capabilities and requiring progressively less data to adapt to unseen epileptic patients. Aiming at providing a more adapted initial condition as well as enhancing the initial training progress of seizure detectors for new patients, this proposal will make use of two machine learning strategies: (1) transfer learning, which explores aspects of the learning process from source-patients in order to improve the detection performance on a target-patient; (2) feature selection for the automatic extraction of highly discriminatory features from normal and abnormal brain activity, also including topological attributes derived from models of brain connection, such as synchronization graphs involving active cerebral regions. Therefore, this proposal does not consider seizure forecasting techniques, being focused only on seizure detection. Initially, open databases available for scientific investigation, such as the Physionet platform, will be the main source of data. However, it is not discarded the cooperation with other research groups associated with the CEPID/Fapesp BRAINN project, to which this proposal is linked.

Academic Publications
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