Fabrication of portable paper-based analytical devices with electrochemical and colorimetric detection system aiming at forensic, clinical, and environmental applications

• Grant number: 16/16477-9
• Support Opportunities: Scholarships in Brazil - Post-Doctorate
• Effective date (Start): February 01, 2017
• Effective date (End): October 31, 2018
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Acordo de Cooperação: Coordination of Improvement of Higher Education Personnel (CAPES)
• Principal Investigator: Lucio Angnes
• Grantee: William Reis de Araujo
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Currently the development of paper-based analytical sensors has gained great prominence in analytical chemistry due to its portability, easy operation and low cost and attracting the interest for several applications in forensic, clinical and environmental areas. However, as a recent research area there is much to be done regarding the development of new sensors and combination different detection techniques to enhancing and increase its applications. Hence, this project aims to develop new sensors on paper substrate combining electrochemical and colorimetric detection for remote applications in different areas (forensics, clinical/medical and environmental). It is intended to combine the portability of these techniques with their robustness for a wide range of analytes. Proposed sensors will always be constructed taking into account that the methodology applied will be easily spread, reproducible and cheap, being attractive for field applications requiring low laboratorial infrastructure and no highly trained staff. (AU)

Scientific publications

(12)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DE ARAUJO, WILLIAM R.; CARDOSO, THIAGO M. G.; DA ROCHA, RAQUEL G.; SANTANA, MARIO H. P.; MUNOZ, RODRIGO A. A.; RICHTER, EDUARDO M.; PAIXAO, THIAGO R. L. C.; COLTRO, WENDELL K. T.. Portable analytical platforms for forensic chemistry: A review. Analytica Chimica Acta, v. 1034, p. 1-21, NOV 30 2018. (17/10522-5, 16/16477-9)

DA SILVA, GABRIELA O.; DE ARAUJO, WILLIAM R.; PAIXAO, THIAGO R. L. C.. Portable and low-cost colorimetric office paper-based device for phenacetin detection in seized cocaine samples. Talanta, v. 176, p. 674-678, JAN 1 2018. (17/10522-5, 11/19903-5, 16/16477-9)

ROCHA, DIEGO P.; CARDOSO, RAFAEL M.; TORMIN, THIAGO F.; DE ARAUJO, WILLIAM R.; MUNOZ, RODRIGO A. A.; RICHTER, EDUARDO M.; ANGNES, LUCIO. Batch-injection Analysis Better than ever: New Materials for Improved Electrochemical Detection and On-site Applications. Electroanalysis, v. 30, n. 7, SI, p. 1386-1399, JUL 2018. (16/16477-9)

AMEKU, WILSON A.; DE ARAUJO, WILLIAM R.; RANGEL, CLARA J.; ANDO, ROMULO A.; PAIXAO, THIAGO R. L. C.. Gold Nanoparticle Paper-Based Dual-Detection Device for Forensics Applications. ACS APPLIED NANO MATERIALS, v. 2, n. 9, p. 5460-5468, SEP 2019. (16/21070-5, 17/10522-5, 18/08782-1, 16/16477-9)

DE OLIVEIRA, LUIZA PEREIRA; ROCHA, DIEGO PESSOA; DE ARAUJO, WILLIAM REIS; ABARZA MUNOZ, RODRIGO ALEJANDRO; LONGO CESAR PAIXAO, THIAGO REGIS; SALLES, MAIARA OLIVEIRA. Forensics in hand: new trends in forensic devices (2013-2017). ANALYTICAL METHODS, v. 10, n. 43, NOV 21 2018. (17/10522-5, 16/16477-9)

ATAIDE, VANESSA N.; MENDES, LETICIA F.; GAMA, LILLIA I. L. M.; DE ARAUJO, WILLIAM R.; PAIXAO, THIAGO R. L. C.. Electrochemical paper-based analytical devices: ten years of development. ANALYTICAL METHODS, v. 12, n. 8, p. 1030-1054, FEB 28 2020. (17/10522-5, 18/14462-0, 18/08782-1, 16/16477-9, 19/16491-0)

ATAIDE, VANESSA N.; AMEKU, WILSON A.; BACIL, RAPHAEL R.; ANGNES, LUCIO; DE ARAUJO, WILLIAM R.; PAIXAO, THIAGO R. L. C.. Enhanced performance of pencil-drawn paper-based electrodes by laser-scribing treatment. RSC ADVANCES, v. 11, n. 3, p. 1644-1653, JAN 13 2021. (18/14462-0, 16/21070-5, 18/08782-1, 16/16477-9, 17/10522-5)

FERREIRA, PATRICK CESAR; ATAIDE, VANESSA NEIVA; SILVA CHAGAS, CYRO LUCAS; ANGNES, LUCIO; TOMAZELLI COLTRO, WENDELL KARLOS; LONGO CESAR PAIXAO, THIAGO REGIS; DE ARAUJO, WILLIAM REIS. Wearable electrochemical sensors for forensic and clinical applications. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, v. 119, OCT 2019. (18/14462-0, 17/10522-5, 16/16477-9, 18/08782-1)

MENDES, LETICIA FRANCINE; SOUZA E SILVA, ANGELA RODRIGUES; BACIL, RAPHAEL PRATA; PIRES SERRANO, SILVIA HELENA; ANGNES, LUCIO; LONGO CESAR PAIXAO, THIAGO REGIS; DE ARAUJO, WILLIAM REIS. Forensic electrochemistry: Electrochemical study and quantification of xylazine in pharmaceutical and urine samples. Electrochimica Acta, v. 295, p. 726-734, FEB 1 2019. (17/10522-5, 15/08539-1, 16/16477-9, 12/06642-1)

GUIMARAES SELVA, THIAGO MATHEUS; DE ARAUJO, WILLIAM REIS; BACIL, RAPHAEL PRATA; LONGO CESAR PAIXAO, THIAGO REGIS. Study of Electrochemical Oxidation and Quantification of the Pesticide Pirimicarb Using a Boron-Doped Diamond Electrode. Electrochimica Acta, v. 246, p. 588-596, AUG 20 2017. (16/16477-9, 12/06642-1)

DE ARAUJO, WILLIAM R.; FRASSON, CAROLINA M. R.; AMEKU, WILSON A.; SILVA, JOSE R.; ANGNES, LUCIO; PAIXAO, THIAGO R. L. C.. Single-Step Reagentless Laser Scribing Fabrication of Electrochemical Paper-Based Analytical Devices. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v. 56, n. 47, p. 15113-15117, NOV 20 2017. (17/10522-5, 16/16477-9)

FERREIRA E SILVA, RAFAEL; LONGO CESAR PAIXAO, THIAGO REGIS; TOROSSIAN TORRES, MARCELO DER; DE ARAUJO, WILLIAM REIS. Simple and inexpensive electrochemical paper-based analytical device for sensitive detection of Pseudomonas aeruginosa. SENSORS AND ACTUATORS B-CHEMICAL, v. 308, APR 1 2020. (17/11398-6, 17/10522-5, 18/08782-1, 16/16477-9)