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Preventive measures for dental erosion

Grant number: 15/21552-7
Support type:Scholarships in Brazil - Doctorate
Effective date (Start): March 01, 2017
Effective date (End): April 30, 2018
Field of knowledge:Health Sciences - Dentistry
Principal Investigator:Daniela Rios Honório
Grantee:Franciny Querobim Ionta
Home Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil

Abstract

Due to the high prevalence of dental erosion found in recent years, new therapies have been studied to prevent or inhibit this condition. The aim of this study is to evaluate in situ different alternatives for dental erosion prevention. The specifically topics assessed are: the effect of different types of oil emulsions alone or oil-containing fluoride mouthrinse on erosive tooth wear (subprojects I and II); the protective potential of a aspartame mouthrinse on erosive toothwear (subproject III) and the effectiveness of a dentifrice containing calcium silicate, phosphate and fluoride on erosive tooth wear, considering episodes of erosion and abrasion (subproject IV). For the subproject I, a volunteer will use the palatal device during 2 hours to form the acquired pellicle and then enamel blocks will be treated in vitro with oil emulsions at two different concentrations (5 or 50%) prior to immersion in 0.5% citric acid pH 2.5 for 2 minutes. For subprojects II, III and IV, a pilot study will be carried out to define the number of volunteers needed. In subproject II, the oil emulsion with the best protective potential will be applied alone or added in a fluoride mouthrinse prior to acid challenge (4x per day for 7 days). In subproject III volunteers will use a aspartame mouthrinse prior to acid challenge (4 times per day for 7 days). In subproject IV, the dentifrice containing calcium silicate, phosphate and fluoride will be applied twice-daily (morning and evening) on one side of the appliance and on the other side brushed with the dentifrice, then subjected to acid challenge (4x per day for 7 days) All the subprojects will have negative (water) and positive (stannous fluoride as solution or dentifrice) control. In the subproject I, surface hardness will be measured and in subprojects II, III and IV the profilometry analysis will be done. Statistical analysis of the subprojects will be done adopting significance level of 5%.

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
IONTA, FRANCINY QUEROBIM; DOS SANTOS, NATALIA MELLO; MESQUITA, ISABELA MANIGLIA; DIONISIO, EVANDRO JOSE; CRUVINEL, THIAGO; HONORIO, HEITOR MARQUES; RIOS, DANIELA. Is the dentifrice containing calcium silicate, sodium phosphate, and fluoride able to protect enamel against chemical mechanical wear? An in situ/ex vivo study. CLINICAL ORAL INVESTIGATIONS, v. 23, n. 10, p. 3713-3720, OCT 2019. Web of Science Citations: 0.
IONTA, FRANCINY QUEROBIM; BARROS DE ALENCAR, CATARINA RIBEIRO; DOS SANTOS, NATALIA MELLO; PORTALUPPE BERGANTIN, BIANCA TOZI; VAL, POLIANA PACIFICO; HONORIO, HEITOR MARQUES; DE OLIVEIRA, THAIS MARCHINI; RIOS, DANIELA. Effect of palm oil alone or associated to stannous solution on enamel erosive-abrasive wear: A randomized in situ/ex vivo study. ARCHIVES OF ORAL BIOLOGY, v. 95, p. 68-73, NOV 2018. Web of Science Citations: 0.
IONTA, FRANCINY QUEROBIM; BARROS DE ALENCAR, CATARINA RIBEIRO; VAL, POLIANA PACIFICO; BOTEON, ANA PAULA; JORDAO, MAISA CAMILLO; HONORIO, HEITOR MARQUES; RABELO BUZALAF, MARILIA AFONSO; RIOS, DANIELA. Effect of vegetable oils applied over acquired enamel pellicle on initial erosion. Journal of Applied Oral Science, v. 25, n. 4, p. 420-426, JUL-AUG 2017. Web of Science Citations: 2.
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
IONTA, Franciny Querobim. Preventive measures for dental erosion. 2018. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Odontologia de Bauru Bauru.

Please report errors in scientific publications list by writing to: cdi@fapesp.br.